Thrombin Mediates Migration of Rat Brain Astrocytes via PLC, Ca2+, CaMKII, PKCα, and AP-1-Dependent Matrix Metalloproteinase-9 Expression

Thrombin induced connective tissue growth factor expression in rat vascular smooth muscle cells via the PAR-1/JNK/AP-1 pathway

(2012) Wen-chin Ko et al.   ACTA PHARMACOLOGICA SINICA

The multifunctional Ca2+/calmodulin-dependent kinase II regulates vascular smooth muscle migration through matrix metalloproteinase 9

(2012) Jason A. Scott et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes

(2012) Chih-Chung Lin et al.   Cell Communication and Signaling

Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells

(2012) I-Ta Lee et al.   Cell Communication and Signaling

Pimaric acid from Aralia cordata has an inhibitory effect on TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1

(2012) Seok-Jong Suh et al.   CHEMICO-BIOLOGICAL INTERACTIONS

PPARδ prevents radiation-induced proinflammatory responses in microglia via transrepression of NF-κB and inhibition of the PKCα/MEK1/2/ERK1/2/AP-1 pathway

(2012) Caroline I. Schnegg et al.   FREE RADICAL BIOLOGY AND MEDICINE

MAP kinase signalling cascades and transcriptional regulation

(2012) Shen-Hsi Yang et al.   GENE

Novel Interactions between NFATc1 (Nuclear Factor of Activated T Cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) Mediate G Protein-coupled Receptor Agonist, Thrombin-induced Biphasic Expression of Cyclin D1, with First Phase Influencing Cell Migration and Second Phase Directing Cell Proliferation

(2012) Venkatesh Kundumani-Sridharan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Thrombin induces an inflammatory phenotype in a human brain endothelial cell line

(2012) Leah M. Alabanza et al.   JOURNAL OF NEUROIMMUNOLOGY

NADPH oxidase-mediated redox signal contributes to lipoteichoic acid-induced MMP-9 upregulation in brain astrocytes

(2012) Hsi-Lung Hsieh et al.   Journal of Neuroinflammation

Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes

(2012) Chuen-Mao Yang et al.   Journal of Neuroinflammation

Thrombin induces MCP-1 expression through Rho-kinase and subsequent p38MAPK/NF-κB signaling pathway activation in vascular endothelial cells

(2011) Daiji Kawanami et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thrombin activation of PI3K/PDK1/Akt signaling promotes cyclin D1 upregulation and RPE cell proliferation

(2011) A. Parrales et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Sphingosine 1-phosphate regulates matrix metalloproteinase-9 expression and breast cell invasion through S1P3-G q coupling

(2011) E.-S. Kim et al.   JOURNAL OF CELL SCIENCE

Thrombin-induced Migration and Matrix Metalloproteinase-9 Expression Are Regulated by MAPK and PI3K Pathways in C6 Glioma Cells

(2011) Jiyoung Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by piperine via the inhibition of PKCα/ERK1/2-dependent matrix metalloproteinase-9 expression

(2011) Yong Pil Hwang et al.   TOXICOLOGY LETTERS

The action of thrombin in intracerebral hemorrhage induced brain damage is mediated via PKCα/PKCδ signaling

(2010) Gui-yun Cui et al.   BRAIN RESEARCH

Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase Cα-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated kinase/activat

(2010) Yong P Hwang et al.   BRITISH JOURNAL OF PHARMACOLOGY

TNF-α induces matrix metalloproteinase-9 expression in A549 cells: Role of TNFR1/TRAF2/PKCα-dependent signaling pathways

(2010) I-Ta Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways

(2010) Hsi-Lung Hsieh et al.   Journal of Neuroinflammation

How factors secreted from astrocytes impact myelin repair

(2010) Craig S. Moore et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Blood-brain barrier breakdown and repair by Src after thrombin-induced injury

(2009) Da-Zhi Liu et al.   ANNALS OF NEUROLOGY

Thrombin regulates matrix metalloproteinase-9 expression in human monocytes

(2009) Chi-Jen Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

IL-1β induces MMP-9 expression via a Ca2+-dependent CaMKII/JNK/c-JUN cascade in rat brain astrocytes

(2009) Cheng-Ying Wu et al.   GLIA

β-Adrenergic receptor stimulated Ncx1 upregulation is mediated via a CaMKII/AP-1 signaling pathway in adult cardiomyocytes

(2009) Santhosh K. Mani et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Activation of ROS/NF-κB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1β-treated human tracheal smooth muscle cells

(2009) Shue-Fen Luo et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Activation of protease-activated receptor1 mediates induction of matrix metalloproteinase-9 by thrombin in rat primary astrocytes

(2008) Min Sik Choi et al.   BRAIN RESEARCH BULLETIN