Nitric Oxide in Myogenesis and Therapeutic Muscle Repair

Nitric oxide donor and non steroidal anti inflammatory drugs as a therapy for muscular dystrophies: Evidence from a safety study with pilot efficacy measures in adult dystrophic patients

(2012) Maria Grazia D’Angelo et al.   PHARMACOLOGICAL RESEARCH

Early functional muscle regeneration after myotoxic injury in mice is unaffected by nNOS absence

(2011) Jarrod E. Church et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans

(2011) Filip J. Larsen et al.   Cell Metabolism

Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD

(2011) Christophe Pichavant et al.   MOLECULAR THERAPY

Restoration of the Dystrophin-associated Glycoprotein Complex After Exon Skipping Therapy in Duchenne Muscular Dystrophy

(2011) Sebahattin Cirak et al.   MOLECULAR THERAPY

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

(2011) Dawn E Bowles et al.   MOLECULAR THERAPY

Loss of sarcolemmal nNOS is common in acquired and inherited neuromuscular disorders

(2011) E. L. Finanger Hedderick et al.   NEUROLOGY

Systemic Administration of PRO051 in Duchenne's Muscular Dystrophy

(2011) Nathalie M. Goemans et al.   NEW ENGLAND JOURNAL OF MEDICINE

A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy

(2011) Clara Sciorati et al.   PHARMACOLOGICAL RESEARCH

iNOS Ablation Does Not Improve Specific Force of the Extensor Digitorum Longus Muscle in Dystrophin-Deficient mdx4cv Mice

(2011) Dejia Li et al.   PLoS One

Neuronal Nitric Oxide Synthase-Rescue of Dystrophin/Utrophin Double Knockout Mice does not Require nNOS Localization to the Cell Membrane

(2011) Michelle Wehling-Henricks et al.   PLoS One

Nitric Oxide Sustains Long-Term Skeletal Muscle Regeneration by Regulating Fate of Satellite Cells Via Signaling Pathways Requiring Vangl2 and Cyclic GMP

(2011) Roberta Buono et al.   STEM CELLS

Co-administration of ibuprofen and nitric oxide is an effective experimental therapy for muscular dystrophy, with immediate applicability to humans

(2010) Clara Sciorati et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation

(2010) C De Palma et al.   CELL DEATH AND DIFFERENTIATION

MicroRNAs Involved in Molecular Circuitries Relevant for the Duchenne Muscular Dystrophy Pathogenesis Are Controlled by the Dystrophin/nNOS Pathway

(2010) Davide Cacchiarelli et al.   Cell Metabolism

The role of nitric oxide during healing of trauma to the skeletal muscle

(2010) Lidiane Isabel Filippin et al.   INFLAMMATION RESEARCH

Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans

(2010) Stephen J. Bailey et al.   JOURNAL OF APPLIED PHYSIOLOGY

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells

(2010) Francesco Saverio Tedesco et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuronal NOS is dislocated during muscle atrophy in amyotrophic lateral sclerosis

(2010) Naoki Suzuki et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Nitric oxide regulates the repair of injured skeletal muscle

(2010) Lidiane Isabel Filippin et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Nitric Oxide, Cytochrome C Oxidase, and the Cellular Response to Hypoxia

(2009) Cormac T. Taylor et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

(2009) Fabien Le Grand et al.   Cell Stem Cell

Gene Therapy With the Angiogenic Cytokine Secretoneurin Induces Therapeutic Angiogenesis by a Nitric Oxide–Dependent Mechanism

(2009) Wilfried Schgoer et al.   CIRCULATION RESEARCH

Muscle stem cells

(2009) Frédéric Relaix et al.   CURRENT OPINION IN CELL BIOLOGY

BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration

(2009) Andrew S. Brack et al.   DEVELOPMENTAL BIOLOGY

Nitric oxide deficiency determines global chromatin changes in Duchenne muscular dystrophy

(2009) Claudia Colussi et al.   FASEB JOURNAL

Requirement of Cell Cycle and Apoptosis Regulator 1 for Target Gene Activation by Wnt and β-Catenin and for Anchorage-independent Growth of Human Colon Carcinoma Cells

(2009) Chen-Yin Ou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of a Nitric Oxide-Releasing Analogue of the Muscle Relaxant Guaifenesin for Skeletal Muscle Satellite Cell Myogenesis

(2009) Guqi Wang et al.   MOLECULAR PHARMACEUTICS

MALDI reveals membrane lipid profile reversion in MDX mice

(2009) Farida Benabdellah et al.   NEUROBIOLOGY OF DISEASE

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

Cyclooxygenase-inhibiting nitric oxide donators for osteoarthritis

(2009) John L. Wallace et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

l-Arginine Decreases Inflammation and Modulates the Nuclear Factor-κB/Matrix Metalloproteinase Cascade in Mdx Muscle Fibers

(2008) Karim Hnia et al.   AMERICAN JOURNAL OF PATHOLOGY

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

(2008) Andrew S. Brack et al.   Cell Stem Cell

Niche Regulation of Muscle Satellite Cell Self-Renewal and Differentiation

(2008) Shihuan Kuang et al.   Cell Stem Cell

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

All muscle satellite cells are equal, but are some more equal than others?

(2008) P. S. Zammit   JOURNAL OF CELL SCIENCE

 -catenin promotes self-renewal of skeletal-muscle satellite cells

(2008) A. Perez-Ruiz et al.   JOURNAL OF CELL SCIENCE

Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration

(2008) A. Otto et al.   JOURNAL OF CELL SCIENCE

Sarcolemma-localized nNOS is required to maintain activity after mild exercise

(2008) Yvonne M. Kobayashi et al.   NATURE

Functional Deficits in nNOSμ-Deficient Skeletal Muscle: Myopathy in nNOS Knockout Mice

(2008) Justin M. Percival et al.   PLoS One

HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

(2008) C. Colussi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA