Melatonin as a Neuroprotective Agent in the Rodent Models of Parkinson’s Disease: Is it All Set to Irrefutable Clinical Translation?

Melatonin-mitochondria Interplay in Health and Disease

(2012) Dario Acuna Castroviejo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Melatonin has membrane receptor-independent hypnotic action on neurons: an hypothesis

(2011) James E. Jan et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Nigrostriatal Proteomics of Cypermethrin-Induced Dopaminergic Neurodegeneration: Microglial Activation-Dependent and -Independent Regulations

(2011) Anand Kumar Singh et al.   TOXICOLOGICAL SCIENCES

The Role of Mitochondria in Brain Aging and the Effects of Melatonin

(2010) Germaine Escames et al.   Current Neuropharmacology

Antiinflammatory Activity of Melatonin in Central Nervous System

(2010) Emanuela Esposito et al.   Current Neuropharmacology

Proteomics in Parkinson’s disease: current trends, translational snags and future possibilities

(2010) Garima Srivastava et al.   Expert Review of Proteomics

Fibroblast growth factor 9 upregulates heme oxygenase-1 and γ-glutamylcysteine synthetase expression to protect neurons from 1-methyl-4-phenylpyridinium toxicity

(2010) Jui-Yen Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of cypermethrin on monoamine transporters, xenobiotic metabolizing enzymes and lipid peroxidation in the rat nigrostriatal system

(2010) Manindra Nath Tiwari et al.   FREE RADICAL RESEARCH

Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats

(2010) Ashutosh Kumar et al.   FREE RADICAL RESEARCH

The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6

(2010) Rituraj Niranjan et al.   FREE RADICAL RESEARCH

Psychopharmacological Neuroprotection in Neurodegenerative Disease: Assessing the Preclinical Data

(2010) E. C. Lauterbach et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy

(2010) Chutikorn Nopparat et al.   JOURNAL OF PINEAL RESEARCH

Melatonin attenuates methamphetamine-induced overexpression of pro-inflammatory cytokines in microglial cell lines

(2010) Jiraporn Tocharus et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes

(2010) Pil-Jae Kong et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Melatonin attenuates the amphetamine-induced decrease in vesicular monoamine transporter-2 expression in postnatal rat striatum

(2010) Sujira Mukda et al.   NEUROSCIENCE LETTERS

Potential Influences of Complementary Therapy on Motor and Non-Motor Complications in Parkinsonʼs Disease

(2009) Theresa A. Zesiewicz et al.   CNS DRUGS

Melatonin and its brain metabolite N1-acetyl-5-methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice

(2009) Víctor Tapias et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model

(2009) Victor Tapias et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Melatonin inhibits 6-hydroxydopamine production in the brain to protect against experimental parkinsonism in rodents

(2009) Anupom Borah et al.   JOURNAL OF PINEAL RESEARCH

Melatonin reduces induction of Bax, caspase and cell death in methamphetamine-treated human neuroblastoma SH-SY5Y cultured cells

(2009) Wilaiwan Wisessmith et al.   JOURNAL OF PINEAL RESEARCH

Visualization of melatonin’s multiple mitochondrial levels of protection against mitochondrial Ca2+-mediated permeability transition and beyond in rat brain astrocytes

(2009) Mei-Jie Jou et al.   JOURNAL OF PINEAL RESEARCH

The protective effect of melatonin on methamphetamine-induced calpain-dependent death pathway in human neuroblastoma SH-SY5Y cultured cells

(2009) Wilasinee Suwanjang et al.   JOURNAL OF PINEAL RESEARCH

Melatonin attenuates methamphetamine-induced reduction of tyrosine hydroxylase, synaptophysin and growth-associated protein-43 levels in the neonatal rat brain

(2009) Sukit Kaewsuk et al.   NEUROCHEMISTRY INTERNATIONAL

Intraocular microinjections repair experimental Parkinson's disease

(2008) Gregory L. Willis   BRAIN RESEARCH

Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats

(2008) Caroline Capitelli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells

(2008) Patthara Kongsuphol et al.   JOURNAL OF PINEAL RESEARCH

Gene Expression Profiles of Mouse Striatum in Control and Maneb + Paraquat-induced Parkinson’s Disease Phenotype: Validation of Differentially Expressed Energy Metabolizing Transcripts

(2008) Suman Patel et al.   MOLECULAR BIOTECHNOLOGY

Oxidative and Inflammatory Pathways in Parkinson’s Disease

(2008) Rebecca L. Miller et al.   NEUROCHEMICAL RESEARCH

Melatonin inhibits amphetamine-induced increase in α-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK–N–SH cells

(2008) Sirirat Klongpanichapak et al.   NEUROSCIENCE LETTERS

Melatonin inhibits amphetamine-induced nitric oxide synthase mRNA overexpression in microglial cell lines

(2008) Jiraporn Tocharus et al.   NEUROSCIENCE LETTERS

Does melatonin help save dopaminergic cells in MPTP-treated mice?

(2008) Jeannine Ma et al.   PARKINSONISM & RELATED DISORDERS

Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats

(2007) Chun-Hung Lin et al.   JOURNAL OF PINEAL RESEARCH