Perturbation of sphingolipid metabolism induces endoplasmic reticulum stress-mediated mitochondrial apoptosis in budding yeast

Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis

(2012) Doris Berchtold et al.   NATURE CELL BIOLOGY

Loss of Subcellular Lipid Transport Due toARV1Deficiency Disrupts Organelle Homeostasis and Activates the Unfolded Protein Response

(2011) Caryn F. Shechtman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The yeast p24 complex regulates GPI-anchored protein transport and quality control by monitoring anchor remodeling

(2011) Guillaume A. Castillon et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane aberrancy and unfolded proteins activate the endoplasmic reticulum stress sensor Ire1 in different ways

(2011) Thanyarat Promlek et al.   MOLECULAR BIOLOGY OF THE CELL

Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells

(2011) António Daniel Barbosa et al.   MOLECULAR MICROBIOLOGY

Ceramide channels and their role in mitochondria-mediated apoptosis

(2010) Marco Colombini   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial involvement in cell death of non-mammalian eukaryotes

(2010) Eltyeb Abdelwahid et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Sphingolipids and cancer: ceramide and sphingosine-1-phosphate in the regulation of cell death and drug resistance

(2010) Suriyan Ponnusamy et al.   Future Oncology

Developmentally Regulated Ceramide Synthase 6 Increases Mitochondrial Ca2+Loading Capacity and Promotes Apoptosis

(2010) Sergei A. Novgorodov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orm family proteins mediate sphingolipid homeostasis

(2010) David K. Breslow et al.   NATURE

Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

(2010) S. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways

(2009) Can E. Senkal et al.   FASEB JOURNAL

Genomewide Analysis Reveals Novel Pathways Affecting Endoplasmic Reticulum Homeostasis, Protein Modification and Quality Control

(2009) A. Copic et al.   GENETICS

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

(2009) Carlotta Giorgi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

(2009) Sebastian Schuck et al.   JOURNAL OF CELL BIOLOGY

Immobilization of the Glycosylphosphatidylinositol-anchored Gas1 Protein into the Chitin Ring and Septum Is Required for Proper Morphogenesis in Yeast

(2009) Eleonora Rolli et al.   MOLECULAR BIOLOGY OF THE CELL

Functional Interactions between Sphingolipids and Sterols in Biological Membranes Regulating Cell Physiology

(2009) Xue Li Guan et al.   MOLECULAR BIOLOGY OF THE CELL

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

(2009) Renata Sano et al.   MOLECULAR CELL

Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides

(2009) Vanessa Cerantola et al.   MOLECULAR MICROBIOLOGY

Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase

(2009) V. Menuz et al.   SCIENCE

Comprehensive Characterization of Genes Required for Protein Folding in the Endoplasmic Reticulum

(2009) M. C. Jonikas et al.   SCIENCE

Lipid-Induced ER Stress: Synergistic Effects of Sterols and Saturated Fatty Acids

(2009) Ludovic Pineau et al.   TRAFFIC

Reactive oxygen species and yeast apoptosis

(2008) Gabriel G. Perrone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondria-dependent apoptosis in yeast

(2008) C. Pereira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulation of Ceramide Biosynthesis by TOR Complex 2

(2008) Sofia Aronova et al.   Cell Metabolism

Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast

(2008) A. M. Aerts et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Heat shock response relieves ER stress

(2008) Yu Liu et al.   EMBO JOURNAL

Nonapoptotic Death ofSaccharomyces cerevisiaeCells That Is Stimulated by Hsp90 and Inhibited by Calcineurin and Cmk2 in Response to Endoplasmic Reticulum Stresses

(2008) Drew D. Dudgeon et al.   EUKARYOTIC CELL

Fungicidal activity of amiodarone is tightly coupled to calcium influx

(2008) Sabina Muend et al.   FEMS YEAST RESEARCH

Increased Resistance of Complex I Mutants to Phytosphingosine-induced Programmed Cell Death

(2008) Ana Castro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the Endoplasmic Reticulum

(2008) Kentaro Kajiwara et al.   MOLECULAR BIOLOGY OF THE CELL

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An Inositolphosphorylceramide Synthase Is Involved in Regulation of Plant Programmed Cell Death Associated with Defense in Arabidopsis

(2008) W. Wang et al.   PLANT CELL

A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle Dynamics

(2008) Robin E. C. Lee et al.   PLoS One

Isc1p Plays a Key Role in Hydrogen Peroxide Resistance and Chronological Lifespan through Modulation of Iron Levels and Apoptosis

(2007) Teresa Almeida et al.   MOLECULAR BIOLOGY OF THE CELL