Tmc gene therapy restores auditory function in deaf mice

Mutations of TMC1 cause deafness by disrupting mechanoelectrical transduction

(2014) Hiroshi Nakanishi et al.   AURIS NASUS LARYNX

Optogenetic stimulation of the auditory pathway

(2014) Victor H. Hernandez et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrating the active process of hair cells with cochlear function

(2014) A. J. Hudspeth   NATURE REVIEWS NEUROSCIENCE

Transmembrane channel-like (TMC) genes are required for auditory and vestibular mechanosensation

(2014) Yoshiyuki Kawashima et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

A Novel DFNA36 Mutation in TMC1 Orthologous to the Beethoven (Bth) Mouse Associated with Autosomal Dominant Hearing Loss in a Chinese Family

(2014) Yali Zhao et al.   PLoS One

Subunit determination of the conductance of hair-cell mechanotransducer channels

(2014) Maryline Beurg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sound Strategies for Hearing Restoration

(2014) G. S. G. Geleoc et al.   SCIENCE

Gene therapy for deafness

(2013) D C Kohrman et al.   GENE THERAPY

TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear

(2013) Bifeng Pan et al.   NEURON

Restoration of Hearing in the VGLUT3 Knockout Mouse Using Virally Mediated Gene Therapy

(2012) Omar Akil et al.   NEURON

Adeno-associated virus-mediated gene delivery into the scala media of the normal and deafened adult mouse ear

(2011) L A Kilpatrick et al.   GENE THERAPY

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

Muscarinic Signaling in the Cochlea: Presynaptic and Postsynaptic Effects on Efferent Feedback and Afferent Excitability

(2010) S. F. Maison et al.   JOURNAL OF NEUROSCIENCE

Mutations in TMC1 contribute significantly to nonsyndromic autosomal recessive sensorineural hearing loss: A report of five novel mutations

(2009) Aslı Sırmacı et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Gene Transfer in Human Vestibular Epithelia and the Prospects for Inner Ear Gene Therapy

(2008) Bradley W. Kesser et al.   LARYNGOSCOPE