Paroxetine-mediated GRK2 inhibition reverses cardiac dysfunction and remodeling after myocardial infarction

Simultaneous Adrenal and Cardiac G-Protein–Coupled Receptor-G βγ Inhibition Halts Heart Failure Progression

(2014) Fadia A. Kamal et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Contemporary Strategies in the Diagnosis and Management of Heart Failure

(2014) Shannon M. Dunlay et al.   MAYO CLINIC PROCEEDINGS

Prodeath Signaling of G Protein–Coupled Receptor Kinase 2 in Cardiac Myocytes After Ischemic Stress Occurs Via Extracellular Signal–Regulated Kinase-Dependent Heat Shock Protein 90–Mediated Mitochondrial Targeting

(2013) Mai Chen et al.   CIRCULATION RESEARCH

Adrenergic Nervous System in Heart Failure

(2013) Anastasios Lymperopoulos et al.   CIRCULATION RESEARCH

Cardiovascular mechanisms of SSRI drugs and their benefits and risks in ischemic heart disease and heart failure

(2013) Andrade Chittaranjan et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Myocardial Ablation of G Protein–Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway

(2013) Qian Fan et al.   PLoS One

Convergence of G Protein-Coupled Receptor and S-Nitrosylation Signaling Determines the Outcome to Cardiac Ischemic Injury

(2013) Z. M. Huang et al.   Science Signaling

Paroxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial Contractility

(2012) David M. Thal et al.   ACS Chemical Biology

Selective Serotonin Reuptake Inhibitors (SSRIs): Therapeutic Drug Monitoring and Pharmacological Interactions

(2012) R. Mandrioli et al.   CURRENT MEDICINAL CHEMISTRY

AAV6. ARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model

(2012) P. W. J. Raake et al.   EUROPEAN HEART JOURNAL

Paroxetine for the treatment of depression: a critical update

(2012) Sara Gibiino et al.   EXPERT OPINION ON PHARMACOTHERAPY

G Protein–Coupled Receptor Kinase 2 Activity Impairs Cardiac Glucose Uptake and Promotes Insulin Resistance After Myocardial Ischemia

(2011) Michele Ciccarelli et al.   CIRCULATION

Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms

(2010) Henriette Brinks et al.   CIRCULATION RESEARCH

Small Molecule Disruption of Gβγ Signaling Inhibits the Progression of Heart Failure

(2010) Liam M. Casey et al.   CIRCULATION RESEARCH

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

Depression and heart failure: An overview of what we know and don't know

(2010) M. A. SILVER   CLEVELAND CLINIC JOURNAL OF MEDICINE

Myocardial Adeno-Associated Virus Serotype 6–βARKct Gene Therapy Improves Cardiac Function and Normalizes the Neurohormonal Axis in Chronic Heart Failure

(2008) Giuseppe Rengo et al.   CIRCULATION

G Protein–Coupled Receptor Kinase 2 Ablation in Cardiac Myocytes Before or After Myocardial Infarction Prevents Heart Failure

(2008) Philip W. Raake et al.   CIRCULATION RESEARCH