The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1

Molecular effects of cancer-associated somatic mutations on the structural and target recognition properties of Keap1

(2015) Halema Khan et al.   BIOCHEMICAL JOURNAL

Redox-Sensitive Transcription Factor Nrf2 Regulates Vascular Smooth Muscle Cell Migration and Neointimal Hyperplasia

(2013) Takashi Ashino et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proteasomes Activate Aggresome Disassembly and Clearance by Producing Unanchored Ubiquitin Chains

(2013) Rui Hao et al.   MOLECULAR CELL

Oncostatin M Modulates the Mesenchymal-Epithelial Transition of Lung Adenocarcinoma Cells by a Mesenchymal Stem Cell-Mediated Paracrine Effect

(2012) M.-L. Wang et al.   CANCER RESEARCH

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

(2011) David Kaluza et al.   EMBO JOURNAL

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Inhibition of cortactin and SIRT1 expression attenuates migration and invasion of prostate cancer DU145 cells

(2011) Keita Nakane et al.   INTERNATIONAL JOURNAL OF UROLOGY

Cortactin

(2011) Kellye C. Kirkbride et al.   Cell Adhesion & Migration

Discovery of the Negative Regulator of Nrf2, Keap1: A Historical Overview

(2010) Ken Itoh et al.   ANTIOXIDANTS & REDOX SIGNALING

Select Heterozygous Keap1 Mutations Have a Dominant-Negative Effect on Wild-Type Keap1 In Vivo

(2010) T. Suzuki et al.   CANCER RESEARCH

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Increased cell migration and plasticity in Nrf2-deficient cancer cell lines

(2010) G Rachakonda et al.   ONCOGENE

Multidrug-resistant protein-3 gene regulation by the transcription factor Nrf2 in human bronchial epithelial and non-small-cell lung carcinoma

(2009) Christopher M. Mahaffey et al.   FREE RADICAL BIOLOGY AND MEDICINE

Localization of cortactin is associated with colorectal cancer development

(2009) Hirakawa   INTERNATIONAL JOURNAL OF ONCOLOGY

Cytoskeleton alterations in melanoma: aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression

(2009) Xu-Zhi Xu et al.   MODERN PATHOLOGY

Cortactin in tumor invasiveness

(2008) Alissa M. Weaver   CANCER LETTERS

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Deacetylation of cortactin by SIRT1 promotes cell migration

(2008) Y Zhang et al.   ONCOGENE

The actin-binding domain of cortactin is dynamic and unstructured and affects lateral and longitudinal contacts in F-actin

(2008) Alexander Shvetsov et al.   CELL MOTILITY AND THE CYTOSKELETON