Citrate induces apoptosis of the acute monocytic leukemia U937 cell line through regulation of HIF-1α signaling

Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells

(2015) Weibo Luo et al.   Oncotarget

Citrate kills tumor cells through activation of apical caspases

(2012) Björn Kruspig et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Novel molecular mechanisms of antitumor action of dichloroacetate against T cell lymphoma: Implication of altered glucose metabolism, pH homeostasis and cell survival regulation

(2012) Ajay Kumar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Enhancing Mitochondrial Respiration Suppresses Tumor Promoter TPA-Induced PKM2 Expression and Cell Transformation in Skin Epidermal JB6 Cells

(2011) J. A. Wittwer et al.   Cancer Prevention Research

Myc Posttranscriptionally Induces HIF1 Protein and Target Gene Expression in Normal and Cancer Cells

(2011) M. R. Doe et al.   CANCER RESEARCH

PK-M2 Makes Cells Sweeter on HIF1

(2011) Daniel A. Tennant   CELL

Glucose deprivation activates AMPK and induces cell death through modulation of Akt in ovarian cancer cells

(2011) Anna Priebe et al.   GYNECOLOGIC ONCOLOGY

Therapeutic targeting of cancer cell metabolism

(2011) Chi V. Dang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML

(2011) Kalpana Gupta et al.   PLoS One

Biochemical disorders induced by cytotoxic marine natural products in breast cancer cells as revealed by proton NMR spectroscopy-based metabolomics

(2010) Mathilde Bayet-Robert et al.   BIOCHEMICAL PHARMACOLOGY

Expression proteomics of acute promyelocytic leukaemia cells treated with methotrexate

(2010) Nitin Kumar Agarwal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells

(2010) Barbara Chiavarina et al.   CELL CYCLE

Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Barking up the right tree?

(2010) Jean-Pierre Bayley et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Pyruvate kinase type M2: A key regulator of the metabolic budget system in tumor cells

(2010) Sybille Mazurek   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Gene expression profiling of sex differences in HIF1-dependent adaptive cardiac responses to chronic hypoxia

(2010) Romana Bohuslavová et al.   JOURNAL OF APPLIED PHYSIOLOGY

Deregulation of HIF1-alpha and hypoxia-regulated pathways in hepatocellular carcinoma and corresponding non-malignant liver tissue—influence of a modulated host stroma on the prognosis of HCC

(2010) Frank Simon et al.   LANGENBECKS ARCHIVES OF SURGERY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE