Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling

Upregulation of Brain Renin Angiotensin System by 27-Hydroxycholesterol in Alzheimer's Disease

(2018) Laura Mateos et al.   JOURNAL OF ALZHEIMERS DISEASE

Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response

(2017) Stanley M H Chan et al.   ENDOCRINOLOGY

Endoplasmic reticulum stress and eIF2α phosphorylation: The Achilles heel of pancreatic β cells

(2017) Miriam Cnop et al.   Molecular Metabolism

Metabolic Stress and Compromised Identity of Pancreatic Beta Cells

(2017) Avital Swisa et al.   Frontiers in Genetics

Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes

(2016) Francesca Cinti et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Differential regulation of angiotensin converting enzyme 2 and nuclear factor-κB by angiotensin II receptor subtypes in type 2 diabetic kidney

(2015) Anuradha Pandey et al.   BIOCHIMIE

Chronic NF-κB blockade improves renal angiotensin II type 1 receptor functions and reduces blood pressure in Zucker diabetic rats

(2015) Hao Luo et al.   Cardiovascular Diabetology

Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits

(2015) H. Siebe Spijker et al.   DIABETES

Weight Loss Decreases Excess Pancreatic Triacylglycerol Specifically in Type 2 Diabetes

(2015) Sarah Steven et al.   DIABETES CARE

Cardiac-specific suppression of NF-κB signaling prevents diabetic cardiomyopathy via inhibition of the renin-angiotensin system

(2014) Candice M. Thomas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Angiotensin II Induces Interleukin-1β–Mediated Islet Inflammation and β-Cell Dysfunction Independently of Vasoconstrictive Effects

(2014) Nadine S. Sauter et al.   DIABETES

GLP-1 ameliorates the proliferation activity of INS-1 cells inhibited by intermittent high glucose concentrations through the regulation of cyclins

(2014) ZHEN ZHANG et al.   Molecular Medicine Reports

Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways

(2014) Karina Huynh et al.   PHARMACOLOGY & THERAPEUTICS

Expression of Mesenchymal and  -Cell Phenotypic Markers in Islet  -Cells in Recently Diagnosed Diabetes

(2013) M. G. White et al.   DIABETES CARE

Inactivation of specific β cell transcription factors in type 2 diabetes

(2013) Shuangli Guo et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiotensin II Regulates Islet Microcirculation and Insulin Secretion in Mice

(2013) Chieko Ihoriya et al.   MICROCIRCULATION

The role of FOXO1 in β-cell failure and type 2 diabetes mellitus

(2013) Tadahiro Kitamura   Nature Reviews Endocrinology

β-cell dedifferentiation in diabetes is important, but what is it?

(2013) Gordon C Weir et al.   Islets

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Direct renin inhibition prevents cardiac dysfunction in a diabetic mouse model: comparison with an angiotensin receptor antagonist and angiotensin-converting enzyme inhibitor

(2012) Candice M. Thomas et al.   CLINICAL SCIENCE

The Adipose/Circulating Renin-Angiotensin System Cross-Talk Enters a New Dimension

(2012) Justin L. Grobe et al.   HYPERTENSION

An NF-κB pathway–mediated positive feedback loop amplifies Ras activity to pathological levels in mice

(2012) Jaroslaw Daniluk et al.   JOURNAL OF CLINICAL INVESTIGATION

Generation of functional insulin-producing cells in the gut by Foxo1 ablation

(2012) Chutima Talchai et al.   NATURE GENETICS

IκBβ Attenuates Angiotensin II–Induced Cardiovascular Inflammation and Fibrosis in Mice

(2011) Shanqin Xu et al.   HYPERTENSION

Glucagon-like peptide–1 and candesartan additively improve glucolipotoxicity in pancreatic β-cells

(2011) Hong-Wei Wang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Telmisartan attenuates fatty-acid-induced oxidative stress and NAD(P)H oxidase activity in pancreatic β-cells

(2009) Y. Saitoh et al.   DIABETES & METABOLISM

Regulation of Pancreatic Juxtaductal Endocrine Cell Formation by FoxO1

(2009) T. Kitamura et al.   MOLECULAR AND CELLULAR BIOLOGY

p38 MAPK Is a Major Regulator of MafA Protein Stability under Oxidative Stress

(2009) Takuma Kondo et al.   MOLECULAR ENDOCRINOLOGY