The Use of Rule-Based and QSPR Approaches in ADME Profiling: A Case Study on Caco-2 Permeability

QSPR in Oral Bioavailability: Specificity or Integrality?

(2012) M. A. Cabrera-Perez et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The Fraction Dose Absorbed, in Humans, and High Jejunal Human Permeability Relationship

(2012) Arik Dahan et al.   MOLECULAR PHARMACEUTICS

BDDCS Applied to Over 900 Drugs

(2011) Leslie Z. Benet et al.   AAPS Journal

Recent Developments of In Silico Predictions of Oral Bioavailability

(2011) Jingyu Zhu et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

In Silico Prediction of Caco-2 Cell Permeability by a Classification QSAR Approach

(2011) Hai Pham The et al.   Molecular Informatics

Probing the links between in vitro potency, ADMET and physicochemical parameters

(2011) M. Paul Gleeson et al.   NATURE REVIEWS DRUG DISCOVERY

Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data

(2010) M. Gertz et al.   DRUG METABOLISM AND DISPOSITION

Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination

(2010) Manthena V. S. Varma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design

(2010) Freya Klepsch et al.   Molecular Informatics

Using the Golden Triangle to optimize clearance and oral absorption

(2009) Ted W. Johnson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Defining optimum lipophilicity and molecular weight ranges for drug candidates—Molecular weight dependent lower logD limits based on permeability

(2009) Michael J. Waring   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent Advances in Physicochemical and ADMET Profiling in Drug Discovery

(2009) Jianling Wang et al.   CHEMISTRY & BIODIVERSITY

Recent Developments of In Silico Predictions of Intestinal Absorption and Oral Bioavailability

(2009) Tingjun Hou et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Structure – ADME relationship: still a long way to go?

(2008) Tingjun Hou et al.   Expert Opinion on Drug Metabolism & Toxicology

Simulation Modelling of Human Intestinal Absorption using Caco-2 Permeability and Kinetic Solubility Data for Early Drug Discovery

(2008) Simon Thomas et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Variability in Caco-2 and MDCK Cell-Based Intestinal Permeability Assays

(2007) Donna A. Volpe   JOURNAL OF PHARMACEUTICAL SCIENCES