Article
Food Science & Technology
Montse Marques, Marti Nadal, Jose L. Domingo
Summary: Polybrominated diphenyl ethers (PBDEs) are a type of brominated flame-retardants (BFRs) that are mainly introduced to the human body through dietary intake. This review discusses recent studies conducted from 2012 to 2022, which show a general trend of decreasing levels of PBDEs in food and consequently, a decrease in dietary intake. The lack of tolerable daily intakes of PBDEs remains a challenge for assessing the human health risks associated with these compounds.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Article
Chemistry, Analytical
Marija Dvorscak, Karla Jagic, Lucija Besednik, Iva Simic, Darija Klincic
Summary: Microwave-assisted extraction (MAE) is an effective method for extracting organic pollutants from human milk samples. By optimizing extraction conditions such as solvent type and volume, extraction temperature, etc., high-quality extracts can be obtained.
MICROCHEMICAL JOURNAL
(2022)
Article
Environmental Sciences
Allison Kupsco, Andreas Sjodin, Whitney Cowell, Richard Jones, Sharon Oberfield, Shuang Wang, Lori A. Hoepner, Dympna Gallagher, Andrea A. Baccarelli, Jeff Goldsmith, Andrew G. Rundle, Julie B. Herbstman
Summary: Data collected from a birth cohort in New York City revealed that prenatal PBDE exposures were not associated with child growth trajectories in Dominican and African American children. The study found no significant impact of cord levels of individual PBDEs or total PBDE mixture on childhood BMIz. Adjusting for postnatal PBDE exposures did not alter the results.
ENVIRONMENTAL HEALTH
(2022)
Article
Surgery
Timothy M. Ullmann, Heng Liang, Hector Mora, Jacques Greenberg, Katherine D. Gray, Jessica Limberg, Dessislava Stefanova, Xin Zhu, Brendan Finnerty, Toni Beninato, Rasa Zarnegar, Irene Min, Thomas J. Fahey
Summary: The study investigated the effects of polybrominated diphenyl ethers (PBDEs) and tris(2-chloroethyl) phosphate (TCEP) on thyrocytes. PBDEs demonstrated genotoxicity but not cytotoxicity in follicular thyrocytes in vitro. These findings suggest that PBDEs may have carcinogenic potential in human thyroid cells.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Environmental Sciences
Qiong Zhang, Jiajun Peng, Anyan Huang, Shukai Zheng, Xiaoling Shi, Boyu Li, Wenlong Huang, Wei Tan, Xin Wang, Kusheng Wu
Summary: Animal studies have shown that exposure to PBDEs can affect lipid balance, and this study investigated the relationship between PBDEs in adipose tissues and blood lipid metabolism in female patients undergoing plastic surgery. The results indicated that certain PBDE congeners were associated with dyslipidemia and blood pressure alteration, and a non-linear relationship was observed between PBDEs and blood lipid levels.
ENVIRONMENTAL RESEARCH
(2022)
Article
Engineering, Environmental
Yu Han, Jiali Cheng, Lei He, Minna Zhang, Shan Ren, Jiazheng Sun, Xiangyang Xing, Zhenwu Tang
Summary: The study conducted in Tianjin, China, revealed that PBDE concentrations in urban soils have decreased in recent years, primarily originating from local industrial production processes and consumer products. More research is needed to further investigate the changing trend of PBDE pollution and its potential impact on human health.
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
(2021)
Article
Chemistry, Analytical
Rama Shanker Sahu, Yu-huei Peng, Chi-Fong Ko, Tzu-Ho Chou, Hepsiba Niruba Catherine, Chien-ying Yang, Chih-ping Tso, Yuh-fan Su, Yang-hsin Shih
Summary: Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants, have attracted the attention of researchers due to their persistence in the environment and widespread use in consumer products. Described as endocrine-disrupting chemicals, PBDEs' full understanding regarding their environmental behavior and fate remains elusive.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Xinran Guo, Shaohong Peng, Liwang Jiang, Xiaoning Mo, Yunhong Zhu, Yang Liu, Kaihan Cai, Qingbin Song
Summary: Improper disposal of e-waste can lead to environmental pollution and human health risks due to the release of high concentrations of PBDEs. However, recycling waste electronic plastics using solvent processes can help reduce these risks. This study focused on the recycling of HIPS from waste TV sets using d-limonene and n-propanol as solvent and precipitant, respectively. The research investigated the relationship between precipitation conditions and the size of precipitate particles, as well as the effect of these conditions on the removal percentage of PBDEs. The results showed that specific conditions, such as lower HIPS concentration, lower precipitation temperature, higher mass ratio of n-propanol to HIPS solution, and greater stirring speed, can promote the formation of smaller and more uniform precipitate particles, thereby improving the removal percentage of PBDEs.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Engineering, Environmental
Mantong Jin, Ziyu Xu, Shunfei Zhang, Liwei Sun, Jiangfan Wu
Summary: Polybrominated diphenyl ethers (PBDEs) are commonly found in the environment due to the use of brominated flame retardants. This study detected PBDEs in air, dust, and particulate matter samples from bedrooms in Hangzhou, indicating wide occurrence of PBDE pollution in bedrooms. The concentration of PBDEs was highest in dust, followed by air and particulate matter. The main source of PBDEs in residential environments was identified as mattresses, curtains, and mattresses combined with curtains. The study also found that infants had the highest daily exposure dose of PBDEs in the air and particulate matter phases.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Environmental Sciences
Bingmeng Xie, Xueqiong Lin, Kusheng Wu, Jiongyu Chen, Shuyi Qiu, Jianan Luo, Yiteng Huang, Lin Peng
Summary: This study found that certain polybrominated diphenyl ethers (PBDEs) in breast adipose tissues are associated with prognostic biomarkers and progression-free survival of breast cancer patients. Further research is needed for confirmation.
ENVIRONMENTAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Tong Wu, Yu Li, Hailin Xiao, Mingli Fu
Summary: The study used a combination of modification and regulation to control PBDE degradation by plants and microorganisms, finding that adding lipophilic groups through modification can enhance degradation efficiency. Molecular docking methods and 3D-QSAR models were employed to design PBDE derivatives for improved degradation, with optimal regulation achieved through supplying an appropriate amount of carbon dioxide.
Article
Engineering, Environmental
Jie Chen, Wei Wang, Lizhong Zhu
Summary: This study reveals that polybrominated diphenyl ethers (PBDEs) can be transported from roots to shoots in rice plants through an amino acid transporter, which has important implications for the bioaccumulation and health risks of PBDEs in rice. It identifies lysine histidine transporter (LHT) as the carrier protein for PBDEs and demonstrates the potential co-transport of PBDEs, phenylalanine, and tyrosine by LHT. The study also provides a molecular explanation for the bioaccumulation and translocation of PBDEs in rice plants.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Aalekhya Reddam, Andreas Sjodin, Whitney Cowell, Richard Jones, Shuang Wang, Frederica Perera, Julie B. Herbstman, Allison Kupsco
Summary: This study found associations between exposure to polybrominated diphenyl ethers (PBDEs) and birth outcomes in a cohort of Dominican and African American newborns, mainly affecting birth weight and length.
ENVIRONMENTAL RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Jinsong Xue, Qingqing Xiao, Min Zhang, Dan Li, Xiaofei Wang
Summary: Polybrominated diphenyl ethers (PBDEs) are widely used flame retardants found in various materials. They have been detected in soil, air, water, dust, and animal tissues, and are associated with a range of toxic effects on different organ systems. Understanding the mechanisms and potential toxicity of PBDEs is important for developing effective prevention strategies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Wei-Hsiang Chang, Quang-Oai Lu, Hsiu-Ling Chen, Ning-Syuan Hsu, Ching-Chang Lee
Summary: This study aimed to evaluate the impact factors and effectiveness of management policies on the presence of PBDEs in sediment samples in Taiwan over the past 10 years. The results showed that the concentrations of PBDEs in sediment samples notably decreased after the implementation of policies banning PBDEs in Taiwan, and the levels of PBDEs were higher in samples collected during the dry season. The levels of PBDEs in sediment samples were influenced by season, the amount of general waste present, and nearby PBDE-related factories and e-waste recycling facilities.
ENVIRONMENTAL POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Enrico Caruso, Marzia Gariboldi, Alessandro Sangion, Paola Gramatica, Stefano Banfi
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2017)
Article
Chemistry, Multidisciplinary
J. P. Doucet, E. Papa, A. Doucet-Panaye, J. Devillers
SAR AND QSAR IN ENVIRONMENTAL RESEARCH
(2017)
Article
Food Science & Technology
Ester Papa, Alessandro Sangion, Jon A. Arnot, Paola Gramatica
FOOD AND CHEMICAL TOXICOLOGY
(2018)
Article
Chemistry, Analytical
Zhe Li, Emma Undeman, Ester Papa, Michael S. McLachlan
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2018)
Article
Chemistry, Analytical
Paola Gramatica, Ester Papa, Alessandro Sangion
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2018)
Article
Chemistry, Medicinal
J. P. Doucet, A. Doucet-Panaye, E. Papa
MOLECULAR INFORMATICS
(2019)
Editorial Material
Chemistry, Medicinal
Ester Papa, Alessandro Sangion, Nicola Chirico
MOLECULAR INFORMATICS
(2019)
Article
Environmental Sciences
Kamel Mansouri, Nicole Kleinstreuer, Ahmed M. Abdelaziz, Domenico Alberga, Vinicius M. Alves, Patrik L. Andersson, Carolina H. Andrade, Fang Bai, Ilya Balabin, Davide Ballabio, Emilio Benfenati, Barun Bhhatarai, Scott Boyer, Jingwen Chen, Viviana Consonni, Sherif Farag, Denis Fourches, Alfonso T. Garcia-Sosa, Paola Gramatica, Francesca Grisoni, Chris M. Grulke, Huixiao Hong, Dragos Horvath, Xin Hu, Ruili Huang, Nina Jeliazkova, Jiazhong Li, Xuehua Li, Huanxiang Liu, Serena Manganelli, Giuseppe F. Mangiatordi, Uko Maran, Gilles Marcou, Todd Martin, Eugene Muratov, Dac-Trung Nguyen, Orazio Nicolotti, Nikolai G. Nikolov, Ulf Norinder, Ester Papa, Michel Petitjean, Geven Piir, Pavel Pogodin, Vladimir Poroikov, Xianliang Qiao, Ann M. Richard, Alessandra Roncaglioni, Patricia Ruiz, Chetan Rupakheti, Sugunadevi Sakkiah, Alessandro Sangion, Karl-Werner Schramm, Chandrabose Selvaraj, Imran Shah, Sulev Sild, Lixia Sun, Olivier Taboureau, Yun Tang, Igor Tetko, Roberto Todeschini, Weida Tong, Daniela Trisciuzzi, Alexander Tropsha, George Van Den Driessche, Alexandre Varnek, Zhongyu Wang, Eva B. Wedebye, Antony J. Williams, Hongbin Xie, Alexey Zakharov, Ziye Zheng, Richard S. Judson
ENVIRONMENTAL HEALTH PERSPECTIVES
(2020)
Article
Engineering, Environmental
Francesco Galimberti, Angelo Moretto, Ester Papa
Article
Chemistry, Medicinal
Daniele Zarini, Alessandro Sangion, Emanuele Ferri, Enrico Caruso, Sara Zucchi, Alessandro Orro, Ester Papa
CHEMICAL RESEARCH IN TOXICOLOGY
(2020)
Article
Chemistry, Multidisciplinary
Nicola Chirico, Alessandro Sangion, Paola Gramatica, Linda Bertato, Ilaria Casartelli, Ester Papa
Summary: The new software QSARINS-Chem standalone version is a multiplatform tool for the in silico profiling of organic chemicals. Based on the concept of QSARINS-chem module embedded in the QSARINS software, it predicts biotransformation rates and aquatic toxicities, and offers tools for analysis. Additionally, a comprehensive and transparent database of molecular structures is provided.
JOURNAL OF COMPUTATIONAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
L. Bertato, O. Taboureau, N. Chirico, E. Papa
Summary: The assessment of bioaccumulation is crucial in understanding environmental behavior and potential risks. The classification QSAR models developed in this study showed good performance in predicting dietary biomagnification, underscoring the importance of data curation and sharing in supporting risk assessment and chemical screening.
SAR AND QSAR IN ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Enrico Caruso, Miryam C. Malacarne, Emanuela Marras, Ester Papa, Linda Bertato, Stefano Banfi, Marzia B. Gariboldi
BIOORGANIC & MEDICINAL CHEMISTRY
(2020)