Synthesis and Preclinical Evaluation of [18F]FCHC for Neuroimaging of Fatty Acid Amide Hydrolase

Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH

(2013) Enrico Dainese et al.   BIOCHEMICAL JOURNAL

Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase

(2013) Oleg Sadovski et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase

(2013) Justin W. Hicks et al.   NUCLEAR MEDICINE AND BIOLOGY

Positron Emission Tomography Shows Elevated Cannabinoid CB1Receptor Binding in Men with Alcohol Dependence

(2012) Alexander Neumeister et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Mapping Human Brain Fatty Acid Amide Hydrolase Activity with PET

(2012) Pablo M Rusjan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Radiosynthesis and Evaluation of [11C-Carbonyl]-Labeled Carbamates as Fatty Acid Amide Hydrolase Radiotracers for Positron Emission Tomography

(2012) Alan A. Wilson et al.   JOURNAL OF MEDICINAL CHEMISTRY

The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH)

(2012) Marc B. Skaddan et al.   NUCLEAR MEDICINE AND BIOLOGY

Assessment of the pharmacology and tolerability of PF-04457845, an irreversible inhibitor of fatty acid amide hydrolase-1, in healthy subjects

(2011) Gai Ling Li et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

(2011) K. Ahn et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Serotonin derivatives as a new class of non-ATP-competitive receptor tyrosine kinase inhibitors

(2010) Anita Büttner et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The endocannabinoid system and psychiatric disorders

(2010) Daniela Parolaro et al.   EXPERIMENTAL NEUROLOGY

Synthesis of substituted [11C]ureas and [11C]sulphonylureas by Rh(I)-mediated carbonylation

(2010) Ola Åberg et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Genetic Deletion of Fatty Acid Amide Hydrolase Alters Emotional Behavior and Serotonergic Transmission in the Dorsal Raphe, Prefrontal Cortex and Hippocampus

(2010) Francis Rodriguez Bambico et al.   NEUROPSYCHOPHARMACOLOGY

[11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography

(2010) Alan A. Wilson et al.   NUCLEAR MEDICINE AND BIOLOGY

Targeting Fatty Acid Amide Hydrolase (FAAH) to Treat Pain and Inflammation

(2009) Joel E. Schlosburg et al.   AAPS Journal

The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or TRPV1

(2009) CJ Fowler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

(2009) Kay Ahn et al.   CHEMISTRY & BIOLOGY

Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models

(2009) Francis Rodriguez Bambico et al.   CURRENT PHARMACEUTICAL DESIGN

Pain and beyond: fatty acid amides and fatty acid amide hydrolase inhibitors in cardiovascular and metabolic diseases

(2009) Sivaram Pillarisetti et al.   DRUG DISCOVERY TODAY

Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields

(2009) Mikko J. Myllymäki et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, In Vitro and In Vivo Evaluation, and Radiolabeling of Aryl Anandamide Analogues as Candidate Radioligands for In Vivo Imaging of Fatty Acid Amide Hydrolase in the Brain

(2009) Leonie wyffels et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand

(2009) Garth E. Terry et al.   NEUROIMAGE

Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous System

(2008) Kay Ahn et al.   CHEMICAL REVIEWS

Development of Radioligands for In Vivo Imaging of Type 1 Cannabinoid Receptors (CB1) in Human Brain

(2008) Andrew Horti et al.   CURRENT PHARMACEUTICAL DESIGN

Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors

(2007) Fabricio A. Moreira et al.   NEUROPHARMACOLOGY

Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats

(2007) D.T. Malone et al.   NEUROSCIENCE