Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation

Sperm-derived WW domain-binding protein, PAWP, elicits calcium oscillations and oocyte activation in humans and mice

(2014) Mahmoud Aarabi et al.   FASEB JOURNAL

First successful pregnancy in a globozoospermic patient having homozygous mutation in SPATA16

(2014) Nilay Karaca et al.   FERTILITY AND STERILITY

Protein phospholipase C Zeta1 expression in patients with failed ICSI but with normal sperm parameters

(2014) Hoi Chang Lee et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes

(2014) M. Nomikos et al.   MOLECULAR HUMAN REPRODUCTION

Molecular characteristics of horse phospholipase C zeta (PLCζ)

(2013) Kana Sato et al.   ANIMAL SCIENCE JOURNAL

DPY19L2 gene mutations are a major cause of globozoospermia: identification of three novel point mutations

(2013) F. Zhu et al.   MOLECULAR HUMAN REPRODUCTION

Fine Characterisation of a Recombination Hotspot at the DPY19L2 Locus and Resolution of the Paradoxical Excess of Duplications over Deletions in the General Population

(2013) Charles Coutton et al.   PLoS Genetics

Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus

(2012) V. Pierre et al.   DEVELOPMENT

SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia

(2012) Y. Fujihara et al.   DEVELOPMENT

Globozoospermia is mainly due to DPY19L2 deletion via non-allelic homologous recombination involving two recombination hotspots

(2012) Elias ElInati et al.   HUMAN MOLECULAR GENETICS

Motile sperm organelle morphology evaluation-selected globozoospermic human sperm with an acrosomal bud exhibits novel patterns and higher levels of phospholipase C zeta

(2012) J. Kashir et al.   HUMAN REPRODUCTION

MLPA and sequence analysis of DPY19L2 reveals point mutations causing globozoospermia

(2012) C. Coutton et al.   HUMAN REPRODUCTION

A Recurrent Deletion of DPY19L2 Causes Infertility in Man by Blocking Sperm Head Elongation and Acrosome Formation

(2011) Radu Harbuz et al.   AMERICAN JOURNAL OF HUMAN GENETICS

DPY19L2 Deletion as a Major Cause of Globozoospermia

(2011) Isabelle Koscinski et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hsp90b1 knockout targeted to male germline: a mouse model for globozoospermia

(2011) Christophe Audouard et al.   FERTILITY AND STERILITY

Successful childbirth after intracytoplasmic morphologically selected sperm injection without assisted oocyte activation in a patient with globozoospermia

(2011) N. Sermondade et al.   HUMAN REPRODUCTION

A newly discovered mutation in PICK1 in a human with globozoospermia

(2010) Gang Liu et al.   ASIAN JOURNAL OF ANDROLOGY

Species-Specific Differences in the Activity and Nuclear Localization of Murine and Bovine Phospholipase C Zeta 11

(2010) Melissa A. Cooney et al.   BIOLOGY OF REPRODUCTION

Reduced fertilization after ICSI and abnormal phospholipase C zeta presence in spermatozoa from the wobbler mouse

(2010) Elke Heytens et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Acrosomal Swelling and Membrane Docking Are Required for Hybrid Vesicle Formation During the Human Sperm Acrosome Reaction1

(2009) Natalia Zanetti et al.   BIOLOGY OF REPRODUCTION

Reduced amounts and abnormal forms of phospholipase C zeta (PLC ) in spermatozoa from infertile men

(2009) E. Heytens et al.   HUMAN REPRODUCTION

PICK1 deficiency causes male infertility in mice by disrupting acrosome formation

(2009) Nan Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

Complete globozoospermia associated with PLCζ deficiency treated with calcium ionophore and ICSI results in pregnancy

(2009) S.L. Taylor et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Difference in Ca2+ Oscillation-Inducing Activity and Nuclear Translocation Ability of PLCZ1, an Egg-Activating Sperm Factor Candidate, Between Mouse, Rat, Human, and Medaka Fish1

(2008) Masahiko Ito et al.   BIOLOGY OF REPRODUCTION

Phospholipase C zeta undergoes dynamic changes in its pattern of localization in sperm during capacitation and the acrosome reaction

(2008) Claire Young et al.   FERTILITY AND STERILITY

The pattern of localization of the putative oocyte activation factor, phospholipase C , in uncapacitated, capacitated, and ionophore-treated human spermatozoa

(2008) P. Grasa et al.   HUMAN REPRODUCTION

Human sperm devoid of PLC, zeta 1 fail to induce Ca2+ release and are unable to initiate the first step of embryo development

(2008) Sook-Young Yoon et al.   JOURNAL OF CLINICAL INVESTIGATION