Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells

Chemotherapeutic Sensitivity of Testicular Germ Cell Tumors Under Hypoxic Conditions Is Negatively Regulated by SENP1-Controlled Sumoylation of OCT4

(2012) Y.-C. Wu et al.   CANCER RESEARCH

Epithelial Cell Adhesion Molecule (EpCAM) Complex Proteins Promote Transcription Factor-mediated Pluripotency Reprogramming

(2011) Hsiang-Po Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metformin Represses Self-Renewal of the Human Breast Carcinoma Stem Cells via Inhibition of Estrogen Receptor-Mediated OCT4 Expression

(2011) Ji-Won Jung et al.   PLoS One

A potential role for insulin-like growth factor signaling in induction of pluripotent stem cell formation

(2010) Yangxin Li et al.   GROWTH HORMONE & IGF RESEARCH

Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells

(2009) Yoshinori Yoshida et al.   Cell Stem Cell

Pluripotency of mouse spermatogonial stem cells maintained by IGF-1- dependent pathway

(2009) Yen-Hua Huang et al.   FASEB JOURNAL

Human cancers converge at the HIF-2α oncogenic axis

(2009) Aleksandra Franovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EsrrbActivatesOct4Transcription and Sustains Self-renewal and Pluripotency in Embryonic Stem Cells

(2008) Xiaofei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PHDs overactivation during chronic hypoxia "desensitizes" HIF  and protects cells from necrosis

(2008) A. Ginouves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA