A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia

(2013) Begoña Díaz et al.   JOURNAL OF CELL BIOLOGY

Homotypic RANK signaling differentially regulates proliferation, motility and cell survival in osteosarcoma and mammary epithelial cells

(2012) Alexander G. Beristain et al.   JOURNAL OF CELL SCIENCE

Self-Control of HGF Regulation on Human Trophoblast Cell Invasion via Enhancing c-Met Receptor Shedding by ADAM10 and ADAM17

(2012) Yanyan Yang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival

(2012) Anthony Leyme et al.   MOLECULAR BIOLOGY OF THE CELL

Effects of interleukin-6 on extravillous trophoblast invasion in early human pregnancy

(2012) Hedele Champion et al.   MOLECULAR HUMAN REPRODUCTION

Complex patterns of ADAM12 mRNA and protein splice variants in the human placenta

(2011) M. Kokozidou et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

Suppression of Colon Cancer Metastasis by Aes through Inhibition of Notch Signaling

(2011) Masahiro Sonoshita et al.   CANCER CELL

A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia

(2011) N. M. Hunkapiller et al.   DEVELOPMENT

ADAM12 Transmembrane and Secreted Isoforms Promote Breast Tumor Growth

(2011) Roopali Roy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion

(2011) V H Rao et al.   ONCOGENE

The secretion of PAPP-A, ADAM12, and PP13 correlates with the size of the placenta for the first month of pregnancy

(2011) M. Sahraravand et al.   PLACENTA

ADAM17 regulates TNFα production by placental trophoblasts

(2011) R. Ma et al.   PLACENTA

Deep trophoblast invasion and spiral artery remodelling in the placental bed of the chimpanzee

(2011) R. Pijnenborg et al.   PLACENTA

Regulated Expression of ADAMTS-12 in Human Trophoblastic Cells: A Role for ADAMTS-12 in Epithelial Cell Invasion?

(2011) Alexander G. Beristain et al.   PLoS One

HER1 Signaling Mediates Extravillous Trophoblast Differentiation in Humans1

(2010) J.K. Wright et al.   BIOLOGY OF REPRODUCTION

Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity

(2010) Reidar Albrechtsen et al.   EXPERIMENTAL CELL RESEARCH

The Disintegrin-like and Cysteine-rich domains of ADAM-9 Mediate Interactions between Melanoma Cells and Fibroblasts

(2010) Paola Zigrino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pre-eclampsia

(2010) Eric AP Steegers et al.   LANCET

ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity

(2009) Dorte Stautz et al.   EXPERIMENTAL CELL RESEARCH

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

(2008) C. Sahlgren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The “A Disintegrin And Metalloprotease” (ADAM) family of sheddases: Physiological and cellular functions

(2008) Karina Reiss et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY