The optogenetic (r)evolution

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

(2011) Garret D. Stuber et al.   NATURE

Functional identification of an aggression locus in the mouse hypothalamus

(2011) Dayu Lin et al.   NATURE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Ultra light-sensitive and fast neuronal activation with the Ca2+-permeable channelrhodopsin CatCh

(2011) Sonja Kleinlogel et al.   NATURE NEUROSCIENCE

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Optogenetic Long-Term Manipulation of Behavior and Animal Development

(2011) Christian Schultheis et al.   PLoS One

High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

(2011) A. Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Channelrhodopsin with a Red-Shifted Spectrum and Rapid Kinetics from Mesostigma viride

(2011) E. G. Govorunova et al.   mBio

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Multi-array silicon probes with integrated optical fibers: light-assisted perturbation and recording of local neural circuits in the behaving animal

(2010) Sébastien Royer et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil BacteriumBeggiatoa

(2010) Manuela Stierl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substitution of 5-HT1AReceptor Signaling by a Light-activated G Protein-coupled Receptor

(2010) Eugene Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping brain networks in awake mice using combined optical neural control and fMRI

(2010) M. Desai et al.   JOURNAL OF NEUROPHYSIOLOGY

Optogenetic Localization and Genetic Perturbation of Saccade-Generating Neurons in Zebrafish

(2010) P. J. Schoonheim et al.   JOURNAL OF NEUROSCIENCE

Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex

(2010) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

fMRI under the spotlight

(2010) David A. Leopold   NATURE

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

(2010) Jin Hyung Lee et al.   NATURE

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Encoding of conditioned fear in central amygdala inhibitory circuits

(2010) Stephane Ciocchi et al.   NATURE

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

Orderly recruitment of motor units under optical control in vivo

(2010) Michael E Llewellyn et al.   NATURE MEDICINE

Optogenetic control of heart muscle in vitro and in vivo

(2010) Tobias Bruegmann et al.   NATURE METHODS

Tuning arousal with optogenetic modulation of locus coeruleus neurons

(2010) Matthew E Carter et al.   NATURE NEUROSCIENCE

Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

(2010) Martin Hägglund et al.   NATURE NEUROSCIENCE

Ultrafast optogenetic control

(2010) Lisa A Gunaydin et al.   NATURE NEUROSCIENCE

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

(2010) Feng Zhang et al.   Nature Protocols

Opto-Current-Clamp Actuation of Cortical Neurons Using a Strategically Designed Channelrhodopsin

(2010) Lei Wen et al.   PLoS One

Optical activation of lateral amygdala pyramidal cells instructs associative fear learning

(2010) Joshua P. Johansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Type-Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward

(2010) M. K. Lobo et al.   SCIENCE

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning

(2010) I. B. Witten et al.   SCIENCE

Optogenetic Control of Cardiac Function

(2010) A. B. Arrenberg et al.   SCIENCE

Functional Control of Transplantable Human ESC-Derived Neurons Via Optogenetic Targeting

(2010) Jason P. Weick et al.   STEM CELLS

Optogenetic deconstruction of sleep-wake circuitry in the brain

(2010) Antoine Adamantidis   Frontiers in Molecular Neuroscience

Structural Guidance of the Photocycle of Channelrhodopsin-2 by an Interhelical Hydrogen Bond

(2009) Christian Bamann et al.   BIOCHEMISTRY

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue

(2009) Jiayi Zhang et al.   Journal of Neural Engineering

Temporal Dynamics of Neuronal Activation by Channelrhodopsin-2 and TRPA1 Determine Behavioral Output in Drosophila Larvae

(2009) Stefan R. Pulver et al.   JOURNAL OF NEUROPHYSIOLOGY

Characterization of Genome Integrity for Oversized Recombinant AAV Vector

(2009) Biao Dong et al.   MOLECULAR THERAPY

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

The subcellular organization of neocortical excitatory connections

(2009) Leopoldo Petreanu et al.   NATURE

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Optical interrogation of neural circuits in Caenorhabditis elegans

(2009) Zengcai V Guo et al.   NATURE METHODS

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE

Millisecond-Timescale Optical Control of Neural Dynamics in the Nonhuman Primate Brain

(2009) Xue Han et al.   NEURON

Glu 87 of Channelrhodopsin-1 Causes pH-dependent Color Tuning and Fast Photocurrent Inactivation

(2009) Satoshi P. Tsunoda et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Optical control of zebrafish behavior with halorhodopsin

(2009) A. B. Arrenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optical Deconstruction of Parkinsonian Neural Circuitry

(2009) V. Gradinaru et al.   SCIENCE

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Short promoters in viral vectors drive selective expression in mammalian inhibitory neurons, but do not restrict activity to specific inhibitory cell-types

(2009) Jason L. Nathanson   Frontiers in Neural Circuits

Escape Behavior Elicited by Single, Channelrhodopsin-2-Evoked Spikes in Zebrafish Somatosensory Neurons

(2008) Adam D. Douglass et al.   CURRENT BIOLOGY

Molecular Determinants Differentiating Photocurrent Properties of Two Channelrhodopsins fromChlamydomonas

(2008) Hongxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A FLEX Switch Targets Channelrhodopsin-2 to Multiple Cell Types for Imaging and Long-Range Circuit Mapping

(2008) D. Atasoy et al.   JOURNAL OF NEUROSCIENCE

Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration

(2008) Pamela S Lagali et al.   NATURE NEUROSCIENCE

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

(2008) Feng Zhang et al.   NATURE NEUROSCIENCE