Novel potential agents for ulcerative colitis by molecular topology: suppression of IL-6 production in Caco-2 and RAW 264.7 cell lines

Molecular topology as a novel approach for drug discovery

(2012) Jorge Gálvez et al.   Expert Opinion on Drug Discovery

Chemistry Explained by Topology: An Alternative Approach

(2011) Jorge Galvez et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Modeling Natural Anti-Inflammatory Compounds by Molecular Topology

(2011) María Galvez-Llompart et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Topological virtual screening: a way to find new compounds active in ulcerative colitis by inhibiting NF-κB

(2011) María Gálvez-Llompart et al.   MOLECULAR DIVERSITY

Combined Phytochemistry and Chemotaxis Assays for Identification and Mechanistic Analysis of Anti-Inflammatory Phytochemicals in Fallopia japonica

(2011) Ming-Yi Shen et al.   PLoS One

Development of a high-throughput screening assay for cytoprotective agents in rotenone-induced cell death

(2010) Il Sang Yoon et al.   ANALYTICAL BIOCHEMISTRY

Synthesis and biological evaluation of nitrogen-containing benzophenone analogues as TNF-α and IL-6 inhibitors with antioxidant activity

(2010) Babasaheb P. Bandgar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Alkamides from Piper longum and Piper nigrum as Inhibitors of IL-6 action

(2010) Seung-Woong Lee et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Anti-inflammatory effects of iridoid glycosides fraction of Folium syringae leaves on TNBS-induced colitis in rats

(2010) Xin Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators

(2010) Jih-Hwa Guh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Application of Molecular Topology to the Search of Novel NSAIDs: Experimental Validation of Activity

(2010) Maria Galvez-Llompart et al.   Letters in Drug Design & Discovery

Characterization and Online Detection of Surfactin Isomers Based on HPLC-MSn Analyses and Their Inhibitory Effects on the Overproduction of Nitric Oxide and the Release of TNF-α and IL-6 in LPS-Induced Macrophages

(2010) Jin-Shan Tang et al.   Marine Drugs

Inflammatory parameters in Caco-2 cells: Effect of stimuli nature, concentration, combination and cell differentiation

(2010) Jacqueline Van De Walle et al.   TOXICOLOGY IN VITRO

Structural–activity relationship study of highly-functionalized imidazolines as potent inhibitors of nuclear transcription factor-κB mediated IL-6 production

(2009) Daljinder K. Kahlon et al.   BIOORGANIC & MEDICINAL CHEMISTRY

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Novel cytokine-targeted therapies and intestinal inflammation

(2009) Maximilian J Waldner et al.   CURRENT OPINION IN PHARMACOLOGY

Oral Beclomethasone Dipropionate as an Alternative to Systemic Steroids in Mild to Moderate Ulcerative Colitis Not Responding to Aminosalicylates

(2009) Claudio Papi et al.   DIGESTIVE DISEASES AND SCIENCES

A review on molecular topology: applying graph theory to drug discovery and design

(2009) José María Amigó et al.   NATURWISSENSCHAFTEN

Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-α and IL-6 inhibitors

(2008) Sandip B. Bharate et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Some New Trends in Chemical Graph Theory

(2008) Ramón García-Domenech et al.   CHEMICAL REVIEWS

Cytokines: From Gut Inflammation to Colorectal Cancer

(2008) Massimo Fantini et al.   CURRENT DRUG TARGETS

Update on Uses and Properties of Citrus Flavonoids: New Findings in Anticancer, Cardiovascular, and Anti-inflammatory Activity

(2008) O. Benavente-García et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY