Journal
MOLECULAR DIVERSITY
Volume 18, Issue 2, Pages 411-439Publisher
SPRINGER
DOI: 10.1007/s11030-013-9494-2
Keywords
Asymmetric synthesis; Michael addition; C-heteroatom bond formation; Enantioselectivity; Chiral catalyst; Chiral reagent
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Funding
- Alzahra University Research Council
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In this review, we try to highlight the recently reported stereoselective Michael conjugate additions of heteroatom nucleophiles to electron-deficient alkenes. The topic is divided based on the nature of the nucleophile employed (nitrogen-, oxygen-, sulfur-, or phosphorus-centered) and then subdivided to distinguish between catalyst-controlled and substrate/reagent-controlled methods which is necessary to achieve asymmetric synthesis.
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