Synthesis of novel spirooxindolo-pyrrolidines, pyrrolizidines, and pyrrolothiazoles via a regioselective three-component [3+2] cycloaddition and their preliminary antimicrobial evaluation

Preparation, antibacterial evaluation and preliminary structure–activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives

(2012) Liang Ouyang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity

(2012) Gangaru Bhaskar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, antimicrobial, anti-inflammatory and antioxidant activity of novel Spiro (imidazo[4′,5′:4,5′]benzo[1,2-e][1, 4] thiazepine)-9,3′-indolines

(2012) Ravindernath Anisetti et al.   Journal of Sulfur Chemistry

A novel one-pot isocyanide-based four-component reaction: synthesis of highly functionalized 1H-pyrazolo[1,2-b]phthalazine-1,2-dicarboxylates and 1H-pyrazolo[1,2-a]pyridazine-1,2-dicarboxylates

(2012) Sajjad Keshipour et al.   TETRAHEDRON

A novel organocatalytic multi-component reaction: an efficient synthesis of polysubstituted pyrano-fused spirooxindoles

(2012) Zeinab Noroozi Tisseh et al.   TETRAHEDRON LETTERS

Direct construction of novel exo′-selective spiropyrrolidine bisoxindoles via a three-component 1,3-dipolar cycloaddition reaction

(2012) Jie Liu et al.   TETRAHEDRON LETTERS

Synthesis of some novel functionalized dihydropyrido[2,3-d]pyrimidines via an one-pot three-component reaction catalysed by InCl3

(2012) P. Seetham Naidu et al.   TETRAHEDRON LETTERS

A rational approach for the design and synthesis of 1-acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles as a new class of potential non-purine xanthine oxidase inhibitors

(2011) Kunal Nepali et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of indole-based new scaffolds for antimicrobial activities—Identification of promising candidates

(2011) Palwinder Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, molecular modeling and bio-evaluation of cycloalkyl fused 2-aminopyrimidines as antitubercular and antidiabetic agents

(2011) Nimisha Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dynamic combinatorial chemistry as a tool for the design of functional materials and devices

(2011) Emilie Moulin et al.   CHEMICAL SOCIETY REVIEWS

Small-Molecule Inhibitors of p53-MDM2 Interaction: the 2006-2010 Update

(2011) Melissa Millard et al.   CURRENT PHARMACEUTICAL DESIGN

Synthesis and QSAR study of novel cytotoxic spiro[3H-indole-3,2′(1′H)-pyrrolo[3,4-c]pyrrole]-2,3′,5′(1H,2′aH,4′H)-triones

(2011) Adel S. Girgis et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Facile Synthesis of Functionalized Spiropyrrolizidine Oxindoles via a Three-Component Tandem Cycloaddition Reaction

(2011) Yong-Mei Xie et al.   MOLECULES

Design, synthesis, and biological evaluation of a biyouyanagin compound library

(2011) K. C. Nicolaou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antimycobacterial activity of spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrids obtained by a three-component regio- and stereoselective 1,3-dipolar cycloaddition

(2011) Stephen Michael Rajesh et al.   MedChemComm

A facile 1,3-dipolar cycloaddition of azomethine ylides to 2-arylidene-1,3-indanediones: Synthesis of dispiro-oxindolylpyrrolothiazoles and their antimycobacterial evaluation

(2010) Shanmugavel Uma Maheswari et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide

(2010) Arumugam Thangamani   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A regio- and stereoselective 1,3-dipolar cycloaddition for the synthesis of novel spiro-pyrrolothiazolyloxindoles and their antitubercular evaluation

(2010) Pitchaimani Prasanna et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimicrobial activity of highly functionalised novel β-lactam grafted spiropyrrolidines and pyrrolizidines

(2010) Natarajan Arumugam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

3-Alkenyl-oxindoles: Natural Products, Pharmaceuticals, and Recent Synthetic Advances in Tandem/Telescoped Approaches

(2010) Alessia Millemaggi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Identification of the Spiro(oxindole-3,3′-thiazolidine)-Based Derivatives as Potential p53 Activity Modulators

(2010) Isabel Gomez-Monterrey et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antigenotoxic, Antioxidant and Lymphocyte Induction Effects Produced by Pteropodine

(2009) Rogelio Paniagua-Pérez et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

A highly atom economic, chemo-, regio- and stereoselective synthesis and evaluation of spiro-pyrrolothiazoles as antitubercular agents

(2009) Subramanian Vedhanarayanan Karthikeyan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A facile synthesis and antimycobacterial evaluation of novel spiro-pyrido-pyrrolizines and pyrrolidines

(2009) Raju Ranjith Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

Synthesis of novel spiropyrrolizidines as potent antimicrobial agents for human and plant pathogens

(2008) Govindasami Periyasami et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Antimycobacterial Spiro-piperidin-4-ones: An Atom Economic, Stereoselective Synthesis, and Biological Intervention

(2008) Raju Ranjith Kumar et al.   JOURNAL OF MEDICINAL CHEMISTRY