Discovery of indeno[1,2- $$c$$ c ]quinoline derivatives as dual topoisomerases I/II inhibitors: Part 3

Discovery of Indeno[1,2-c]quinoline Derivatives as Inhibitors of Osteoclastogenesis Induced by Receptor Activator of NF-κB Ligand (RANKL)

(2011) Chih-Hua Tseng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship

(2010) Pritam Thapa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure–activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines

(2010) Radha Karki et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and evaluation of 9-benzylideneamino derivatives of homocamptothecin as potent inhibitors of DNA topoisomerase I

(2010) Wei Guo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure-Based Design, Synthesis, and Biological Studies of New Anticancer Norindenoisoquinoline Topoisomerase I Inhibitors

(2010) Yunlong Song et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mitotic Arrest Induced by a Novel Family of DNA Topoisomerase II Inhibitors

(2010) Leticia G. León et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antiproliferative Evaluation of Certain Indeno[1,2-c]quinoline Derivatives. Part 2

(2010) Chih-Hua Tseng et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Series of α-Heterocyclic Carboxaldehyde Thiosemicarbazones Inhibit Topoisomerase IIα Catalytic Activity

(2010) He Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

A New Class of Naphthalimide-Based Antitumor Agents That Inhibit Topoisomerase II and Induce Lysosomal Membrane Permeabilization and Apoptosis

(2010) Zhuo Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents

(2009) Wei Feng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Pyranonaphthoquinone derivatives of eleutherin, ventiloquinone L, thysanone and nanaomycin A possessing a diverse topoisomerase II inhibition and cytotoxicity spectrum

(2009) Jonathan Sperry et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: Investigating the hypothesis of shared structure–activity relationships

(2009) Maris A. Cinelli et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, cytotoxic activity, DNA topoisomerase-II inhibition, molecular modeling and structure–activity relationship of 9-anilinothiazolo[5,4-b]quinoline derivatives

(2009) Marco A. Loza-Mejía et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Furanocoumarins: Novel topoisomerase I inhibitors from Ruta graveolens L.

(2009) Renuka Diwan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide

(2009) Wei Feng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Biological Activities of Topoisomerase I Inhibitors, 6-Arylmethylamino Analogues of Edotecarin

(2009) Satoshi Sunami et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of a Novel Series of Quinolone and Naphthyridine Derivatives as Potential Topoisomerase I Inhibitors by Scaffold Modification

(2009) Qi-Dong You et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays

(2008) Gunes Coban et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Cytotoxicity, DNA Interaction, and Topoisomerase II Inhibition Properties of Novel Indeno[2,1-c]quinolin-7-one and Indeno[1,2-c]isoquinolin-5,11-dione Derivatives

(2008) Adina Ryckebusch et al.   JOURNAL OF MEDICINAL CHEMISTRY