Butein, a novel dual inhibitor of MET and EGFR, overcomes gefitinib-resistant lung cancer growth

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Butein Inhibits the Migration and Invasion of SK-HEP-1 Human Hepatocarcinoma Cells through Suppressing the ERK, JNK, p38, and uPA Signaling Multiple Pathways

(2011) Chia-Yu Ma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

7,3′,4′-Trihydroxyisoflavone, a Metabolite of the Soy Isoflavone Daidzein, Suppresses Ultraviolet B-induced Skin Cancer by Targeting Cot and MKK4

(2011) Dong Eun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells

(2010) Angeline Wei Ling Chua et al.   BIOCHEMICAL PHARMACOLOGY

Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC

(2010) Alexa B. Turke et al.   CANCER CELL

Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo

(2010) Peramaiyan Rajendran et al.   CLINICAL CANCER RESEARCH

Butein downregulates phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in cancerous and non-cancerous breast cells

(2010) Grace Tak Yi Lau et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases

(2009) F. Qian et al.   CANCER RESEARCH

Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors

(2009) A F Gazdar   ONCOGENE

Myricetin Suppresses UVB-Induced Skin Cancer by Targeting Fyn

(2008) S. K. Jung et al.   CANCER RESEARCH