The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic

(2011) Shuliang Chen et al.   MOLECULAR BIOLOGY OF THE CELL

hSulf-1 Gene Exhibits Anticancer Efficacy through Negatively Regulating VEGFR-2 Signaling in Human Cancers

(2011) Weidan Ji et al.   PLoS One

TRAPPC4-ERK2 Interaction Activates ERK1/2, Modulates Its Nuclear Localization and Regulates Proliferation and Apoptosis of Colorectal Cancer Cells

(2011) Shu-Liang Zhao et al.   PLoS One

Targeting the RAS pathway in melanoma

(2011) Zhenyu Ji et al.   TRENDS IN MOLECULAR MEDICINE

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy

(2010) Molly A. Lynch-Day et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Truncating Mutation of TRAPPC9 Is Associated with Autosomal-Recessive Intellectual Disability and Postnatal Microcephaly

(2009) Ganeshwaran H. Mochida et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Crystal structure of human synbindin reveals two conformations of longin domain

(2008) Shilong Fan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology

(2008) H Brenner et al.   BRITISH JOURNAL OF CANCER

Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR–ERK activation in renal cell carcinoma

(2008) Lei Li et al.   CANCER LETTERS

The TRAPP Complex: Insights into its Architecture and Function

(2008) Michael Sacher et al.   TRAFFIC