Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest

Title
Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest
Authors
Keywords
-
Journal
MOLECULAR CANCER THERAPEUTICS
Volume 7, Issue 2, Pages 252-262
Publisher
American Association for Cancer Research (AACR)
Online
2008-02-16
DOI
10.1158/1535-7163.mct-07-2066

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