Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase a oncogene

Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer

(2011) Hernan Carol et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

SLAIN2 links microtubule plus end–tracking proteins and controls microtubule growth in interphase

(2011) Babet van der Vaart et al.   JOURNAL OF CELL BIOLOGY

Polo-Like Kinase 1 is a Therapeutic Target in High-Risk Neuroblastoma

(2010) S. Ackermann et al.   CLINICAL CANCER RESEARCH

High resolution ArrayCGH and expression profiling identifies PTPRD and PCDH17/PCH68 as tumor suppressor gene candidates in laryngeal squamous cell carcinoma

(2010) Maciej Giefing et al.   GENES CHROMOSOMES & CANCER

Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis

(2010) Derek M. Murphy et al.   MOLECULAR CARCINOGENESIS

Stabilization of N-Myc Is a Critical Function of Aurora A in Human Neuroblastoma

(2009) Tobias Otto et al.   CANCER CELL

Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma

(2009) X. Shang et al.   MOLECULAR CANCER THERAPEUTICS

Distinct High-Profile Methylated Genes in Colorectal Cancer

(2009) Pooneh Mokarram et al.   PLoS One

Global MYCN Transcription Factor Binding Analysis in Neuroblastoma Reveals Association with Distinct E-Box Motifs and Regions of DNA Hypermethylation

(2009) Derek M. Murphy et al.   PLoS One

Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma

(2008) D. A. Solomon et al.   CANCER RESEARCH

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

Aberrant splicing of thePTPRDgene mimics microdeletions identified at this locus in neuroblastomas

(2007) Prakash Nair et al.   GENES CHROMOSOMES & CANCER