A MCP1 fusokine with CCR2-specific tumoricidal activity

A Fusion of GMCSF and IL-21 Initiates Hypersignaling Through the IL-21Rα Chain With Immune Activating and Tumoricidal Effects In Vivo

(2010) Patrick Williams et al.   MOLECULAR THERAPY

A Destructive Cascade Mediated by CCL2 Facilitates Prostate Cancer Growth in Bone

(2009) Xin Li et al.   CANCER RESEARCH

Selective Inhibition of CCR2 Expressing Lymphomyeloid Cells in Experimental Autoimmune Encephalomyelitis by a GM-CSF-MCP1 Fusokine

(2009) M. Rafei et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal Stromal Cells Ameliorate Experimental Autoimmune Encephalomyelitis by Inhibiting CD4 Th17 T Cells in a CC Chemokine Ligand 2-Dependent Manner

(2009) Moutih Rafei et al.   JOURNAL OF IMMUNOLOGY

Predominant Expression of CCL2 at the Tumor Site of Prostate Cancer Patients Directs a Selective Loss of Immunological Tolerance to CCL2 That Could Be Amplified in a Beneficial Manner

(2009) L. Izhak et al.   JOURNAL OF IMMUNOLOGY

A granulocyte-macrophage colony–stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties

(2009) Moutih Rafei et al.   NATURE MEDICINE

Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment

(2008) Morgan O'Hayre et al.   BIOCHEMICAL JOURNAL

TGFβ secreted by B16 melanoma antagonizes cancer gene immunotherapy bystander effect

(2008) Claudia Penafuerte et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Neo-Organoid of Marrow Mesenchymal Stromal Cells Secreting Interleukin-12 for Breast Cancer Therapy

(2008) N. Eliopoulos et al.   CANCER RESEARCH

The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread

(2008) B. A. Hatton et al.   CANCER RESEARCH

Coupling erythropoietin secretion to mesenchymal stromal cells enhances their regenerative properties

(2008) Ian B. Copland et al.   CARDIOVASCULAR RESEARCH

Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone

(2008) Yi Lu et al.   CLINICAL & EXPERIMENTAL METASTASIS