Recombinant Deamidated Mutants of Erwinia chrysanthemi l-Asparaginase Have Similar or Increased Activity Compared to Wild-Type Enzyme

Nanostructure l-asparaginase-fatty acid bioconjugate: Synthesis, preformulation study and biological assessment

(2013) Hajar Ashrafi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

BeAtMuSiC: prediction of changes in protein–protein binding affinity on mutations

(2013) Yves Dehouck et al.   NUCLEIC ACIDS RESEARCH

Control of process-induced asparaginyl deamidation during manufacture of Erwinia chrysanthemi l-asparaginase

(2013) David Gervais et al.   PROCESS BIOCHEMISTRY

Structural and Functional Role of Gly281 in L-asparaginase from Erwinia carotovora

(2013) Georgia Kotzia et al.   PROTEIN AND PEPTIDE LETTERS

Validation of a 30-year-old process for the manufacture of l-asparaginase from Erwinia chrysanthemi

(2012) David Gervais et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

COFACTOR: an accurate comparative algorithm for structure-based protein function annotation

(2012) Ambrish Roy et al.   NUCLEIC ACIDS RESEARCH

Proteins from Erwinia asparaginase Erwinase® and E. coli asparaginase 2 MEDAC® for treatment of human leukemia, show a multitude of modifications for which the consequences are completely unclear

(2011) Narkhyun Bae et al.   ELECTROPHORESIS

Isolation and characterization of therapeutic antibody charge variants using cation exchange displacement chromatography

(2011) Taylor Zhang et al.   JOURNAL OF CHROMATOGRAPHY A

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

L-asparaginase treatment in acute lymphoblastic leukemia

(2010) Rob Pieters et al.   CANCER

Structure-Function Relationships and Clinical Applications of L-Asparaginases

(2010) N.E. Labrou et al.   CURRENT MEDICINAL CHEMISTRY

Charge variants in IgG1

(2010) Leslie A. Khawli et al.   mAbs

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

AUTO-MUTE: web-based tools for predicting stability changes in proteins due to single amino acid replacements

(2010) M. Masso et al.   PROTEIN ENGINEERING DESIGN & SELECTION

I-TASSER server for protein 3D structure prediction

(2008) Yang Zhang   BMC BIOINFORMATICS

Structural and functional insights into Erwinia carotovora l-asparaginase

(2008) Anastassios C. Papageorgiou et al.   FEBS Journal

Deamidation destabilizes and triggers aggregation of a lens protein, βA3-crystallin

(2008) Takumi Takata et al.   PROTEIN SCIENCE

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS