Generation and Comparative Characterization of Glycosylated and Aglycosylated Human IgG1 Antibodies

Bypassing glycosylation: engineering aglycosylated full-length IgG antibodies for human therapy

(2011) Sang Taek Jung et al.   CURRENT OPINION IN BIOTECHNOLOGY

Acid-Induced Aggregation of Human Monoclonal IgG1 and IgG2: Molecular Mechanism and the Effect of Solution Composition

(2010) Sanjay B. Hari et al.   BIOCHEMISTRY

Influence of pH on Heat-Induced Aggregation and Degradation of Therapeutic Monoclonal Antibodies

(2010) Tomoyoshi Ishikawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Glycosylation influences on the aggregation propensity of therapeutic monoclonal antibodies

(2010) Veysel Kayser et al.   Biotechnology Journal

Recombinant antibodies: Engineering and production in yeast and bacterial hosts

(2010) Ki Jun Jeong et al.   Biotechnology Journal

Formulation Development of Therapeutic Monoclonal Antibodies Using High-Throughput Fluorescence and Static Light Scattering Techniques: Role of Conformational and Colloidal Stability

(2010) Deborah S. Goldberg et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Stability of IgG isotypes in serum

(2010) Ivan Correia   mAbs

Specific interactions in high concentration antibody solutions resulting in high viscosity

(2009) Sandeep Yadav et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action

(2009) Royston Jefferis   TRENDS IN PHARMACOLOGICAL SCIENCES

Plants as biofactories

(2008) Vadim Mett et al.   BIOLOGICALS

Meeting report & News from academia

(2008) Sandrine Moutel et al.   Biotechnology Journal

Reversible Self-Association of a Concentrated Monoclonal Antibody Solution Mediated by Fab–Fab Interaction That Impacts Solution Viscosity

(2008) Sonoko Kanai et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effect of Ions on Agitation- and Temperature-Induced Aggregation Reactions of Antibodies

(2008) R. Matthew Fesinmeyer et al.   PHARMACEUTICAL RESEARCH

Aglycosylated immunoglobulin G1 variants productively engage activating Fc receptors

(2008) S. L. Sazinsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of constant and variable domain glycosylation on pharmacokinetics of therapeutic antibodies in mice

(2007) Thomas A. Millward et al.   BIOLOGICALS