Strategies of Bacterial Over Expression of Membrane Transporters Relevant in Human Health: The Successful Case of the Three Members of OCTN Subfamily

Over-expression in Escherichia coli, purification and reconstitution in liposomes of the third member of the OCTN sub-family: The mouse carnitine transporter OCTN3

(2012) Mariafrancesca Scalise et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed inEscherichia coli

(2011) Lorena Pochini et al.   BIOCHEMICAL JOURNAL

The role of amino acid transporters in inherited and acquired diseases

(2011) Stefan Bröer et al.   BIOCHEMICAL JOURNAL

Folding and stability of membrane transport proteins in vitro

(2011) Nicola J. Harris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease

(2011) Lorena Pochini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The P-glycoprotein multidrug transporter

(2011) Frances J. Sharom   Essays in Biochemistry

Role of organic cation transporters in drug-induced toxicity

(2011) Giuliano Ciarimboli   Expert Opinion on Drug Metabolism & Toxicology

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients

(2011) Maurizio Martini et al.   INFLAMMATORY BOWEL DISEASES

Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis

(2011) Chao Xuan et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Consequences of the Overexpression of a Eukaryotic Membrane Protein, the Human KDEL Receptor, in Escherichia coli

(2011) Mirjam M. Klepsch et al.   JOURNAL OF MOLECULAR BIOLOGY

Solute Carrier Transporters as Targets for Drug Delivery and Pharmacological Intervention for Chemotherapy

(2011) Takeo Nakanishi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Over-Expression in E. coli and Purification of the Human OCTN2 Transport Protein

(2011) Michele Galluccio et al.   MOLECULAR BIOTECHNOLOGY

A Gene Optimization Strategy that Enhances Production of Fully Functional P-Glycoprotein in Pichia pastoris

(2011) Jiangping Bai et al.   PLoS One

High-yield production, purification and characterization of functional human duodenal cytochrome b in an Escherichia coli system

(2011) Wen Liu et al.   PROTEIN EXPRESSION AND PURIFICATION

The structural basis of secondary active transport mechanisms

(2010) Lucy R. Forrest et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Glycosylation of the OCTN2 carnitine transporter: Study of natural mutations identified in patients with primary carnitine deficiency

(2010) Cristina Amat di San Filippo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Wheat-Germ Cell-Free Expression System

(2010) Kazuyuki Takai et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Combinatorial Method for Overexpression of Membrane Proteins inEscherichia coli

(2010) Shani Leviatan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Side effects of chaperone gene co-expression in recombinant protein production

(2010) Mónica Martínez-Alonso et al.   Microbial Cell Factories

Crystal structure of the carnitine transporter and insights into the antiport mechanism

(2010) Lin Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural perspectives on secondary active transporters

(2010) Olga Boudker et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

(2009) Arianna Rath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Over-expression in E. coli and purification of the human OCTN1 transport protein

(2009) Michele Galluccio et al.   PROTEIN EXPRESSION AND PURIFICATION

Bacterial expression of a eukaryotic membrane protein in fusion to various Mistic orthologs

(2009) Hay Dvir et al.   PROTEIN EXPRESSION AND PURIFICATION

Cell Free Expression and Functional Reconstitution of Eukaryotic Drug Transporters†

(2008) Thorsten Keller et al.   BIOCHEMISTRY

Diseases caused by defects of mitochondrial carriers: A review

(2008) Ferdinando Palmieri   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

High yield cell-free production of integral membrane proteins without refolding or detergents

(2008) Jessica J. Wuu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans

(2008) I Wessler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inactivation by omeprazole of the carnitine transporter (OCTN2) reconstituted in liposomes

(2008) Lorena Pochini et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Role of Na+/L-carnitine Transporter (OCTN2) in Renal Handling of Pivaloylcarnitine and Valproylcarnitine Formed during Pivalic Acid-containing Prodrugs and Valproic Acid Treatment

(2008) Shuichi Ohnishi et al.   Drug Metabolism and Pharmacokinetics

Tuning Escherichia coli for membrane protein overexpression

(2008) S. Wagner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression patterns of the organic cation/carnitine transporter family in adult murine brain

(2007) Anne Marie Lamhonwah et al.   BRAIN & DEVELOPMENT

Efficiency of cell-free protein synthesis based on a crude cell extract from Escherichia coli, wheat germ, and rabbit reticulocytes

(2007) Mami Hino et al.   JOURNAL OF BIOTECHNOLOGY