Intrinsic disorder in the androgen receptor: identification, characterisation and drugability

Mechanism of Androgen Receptor Antagonism by Bicalutamide in the Treatment of Prostate Cancer

(2011) D. J. Osguthorpe et al.   BIOCHEMISTRY

Lysine Methylation and Functional Modulation of Androgen Receptor by Set9 Methyltransferase

(2011) Soyoung Ko et al.   MOLECULAR ENDOCRINOLOGY

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

(2011) Natacha Rochel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex

(2011) Jun Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival

(2011) Emma Hörnberg et al.   PLoS One

Androgens and the male reproductive tract: an overview of classical roles and current perspectives

(2010) Marilia T. C. C. Patrão et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Regression of Castrate-Recurrent Prostate Cancer by a Small-Molecule Inhibitor of the Amino-Terminus Domain of the Androgen Receptor

(2010) Raymond J. Andersen et al.   CANCER CELL

The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process

(2010) Pierre Chymkowitch et al.   EMBO JOURNAL

Green tea polyphenol EGCG blunts androgen receptor function in prostate cancer

(2010) Imtiaz A. Siddiqui et al.   FASEB JOURNAL

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

(2010) Shihua Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

FKBP51 Promotes Assembly of the Hsp90 Chaperone Complex and Regulates Androgen Receptor Signaling in Prostate Cancer Cells

(2010) L. Ni et al.   MOLECULAR AND CELLULAR BIOLOGY

The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth

(2010) Daniela Roell et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of the androgen receptor by SET9-mediated methylation

(2010) Luke Gaughan et al.   NUCLEIC ACIDS RESEARCH

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

(2010) P. A. Watson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of androgen receptor phosphorylation in the primate ovary in vivo

(2010) Iain J McEwan et al.   REPRODUCTION

Development of Androgen Receptor Antagonists with Promising Activity in Castration-Resistant Prostate Cancer

(2009) Howard C. Shen et al.   CANCER CELL

Molecular mechanisms of castration-resistant prostate cancer progression

(2009) Smitha S Dutt et al.   Future Oncology

NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth

(2009) Maria Papaioannou et al.   INVESTIGATIONAL NEW DRUGS

Site-Specific Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor

(2009) A. M. S. Garza et al.   MOLECULAR AND CELLULAR BIOLOGY

Non-competitive androgen receptor inhibition in vitro and in vivo

(2009) J. O. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

(2009) C. Tran et al.   SCIENCE

A Cellular Conformation-Based Screen for Androgen Receptor Inhibitors

(2008) Jeremy O. Jones et al.   ACS Chemical Biology

Functional Characterization of the Native NH2-Terminal Transactivation Domain of the Human Androgen Receptor: Binding Kinetics for Interactions with TFIIF and SRC-1a†

(2008) Derek N. Lavery et al.   BIOCHEMISTRY

Structural Characterization of the Native NH2-Terminal Transactivation Domain of the Human Androgen Receptor: A Collapsed Disordered Conformation Underlies Structural Plasticity and Protein-Induced Folding†

(2008) Derek N. Lavery et al.   BIOCHEMISTRY

Phosphorylation of the androgen receptor is associated with reduced survival in hormone-refractory prostate cancer patients

(2008) P McCall et al.   BRITISH JOURNAL OF CANCER

Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor that Mediates Prostate Cancer Therapy Resistance

(2008) S. M. Dehm et al.   CANCER RESEARCH

Site-specific Androgen Receptor Serine Phosphorylation Linked to Epidermal Growth Factor-dependent Growth of Castration-recurrent Prostate Cancer

(2008) Liliana A. Ponguta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for the nuclear import of the human androgen receptor

(2008) M. L. Cutress et al.   JOURNAL OF CELL SCIENCE

Consequences of poly-glutamine repeat length for the conformation and folding of the androgen receptor amino-terminal domain

(2008) Philippa Davies et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Minireview: The Contribution of Different Androgen Receptor Domains to Receptor Dimerization and Signaling

(2008) Margaret M. Centenera et al.   MOLECULAR ENDOCRINOLOGY

Glucocorticoid Receptor Phosphorylation Differentially Affects Target Gene Expression

(2008) Weiwei Chen et al.   MOLECULAR ENDOCRINOLOGY

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE

Sintokamides A to E, Chlorinated Peptides from the SpongeDysideasp. that Inhibit Transactivation of the N-Terminus of the Androgen Receptor in Prostate Cancer Cells

(2008) Marianne D. Sadar et al.   ORGANIC LETTERS