Parallel tracking of cAMP and PKA signaling dynamics in living cells with FRET-based fluorescent biosensors

Reporting from the Field: Genetically Encoded Fluorescent Reporters Uncover Signaling Dynamics in Living Biological Systems

(2011) Sohum Mehta et al.   Annual Review of Biochemistry

Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells

(2011) Robert H. Newman et al.   CHEMICAL REVIEWS

Direct Activation of Epac by Sulfonylurea Is Isoform Selective

(2011) Katie J. Herbst et al.   CHEMISTRY & BIOLOGY

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

(2011) Sebastian Börner et al.   Nature Protocols

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Simultaneous Visualization of Protumorigenic Src and MT1-MMP Activities with Fluorescence Resonance Energy Transfer

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Visualization of PKA activity in plasma membrane microdomains

(2010) Charlene Depry et al.   Molecular BioSystems

Signaling diversity of PKA achieved via a Ca2+-cAMP-PKA oscillatory circuit

(2010) Qiang Ni et al.   Nature Chemical Biology

Decoding signalling networks by mass spectrometry-based proteomics

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B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression

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Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposure

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The structure and function of fluorescent proteins

(2009) Vedangi Sample et al.   CHEMICAL SOCIETY REVIEWS

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(2009) Wolf B. Frommer et al.   CHEMICAL SOCIETY REVIEWS

The fluorescent protein palette: tools for cellular imaging

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Dynamic visualization of signal transduction in living cells: From second messengers to kinases

(2009) Katie J. Herbst et al.   IUBMB LIFE

The role of membrane microdomains in shaping β2-adrenergic receptor-mediated cAMP dynamics

(2009) Lisa M. DiPilato et al.   Molecular BioSystems

An ultramarine fluorescent protein with increased photostability and pH insensitivity

(2009) Wataru Tomosugi et al.   NATURE METHODS

Simultaneous Live Cell Imaging Using Dual FRET Sensors with a Single Excitation Light

(2009) Yusuke Niino et al.   PLoS One

Simultaneous Recording of Multiple Cellular Events by FRET

(2008) Alen Piljic et al.   ACS Chemical Biology

Multiplexed FRET to Image Multiple Signaling Events in Live Cells

(2008) David M. Grant et al.   BIOPHYSICAL JOURNAL

Fluorescent biosensors of protein function

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Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors

(2008) Hui-wang Ai et al.   NATURE METHODS

A Tunable FRET Circuit for Engineering Fluorescent Biosensors

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Signaling through cAMP and cAMP-dependent protein kinase: Diverse strategies for drug design

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