Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2

(2010) Zachary Charlop-Powers et al.   CELL RESEARCH

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

(2010) Takashi Umehara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

A Novel Translocation Breakpoint within the BPTF Gene Is Associated with a Pre-Malignant Phenotype

(2010) Yosef Buganim et al.   PLoS One

Current Screens Based on the AlphaScreen™ Technology for Deciphering Cell Signalling Pathways

(2009) Said Taouji et al.   CURRENT GENOMICS

Proteasomal Degradation of the Papillomavirus E2 Protein Is Inhibited by Overexpression of Bromodomain-Containing Protein 4

(2009) D. Gagnon et al.   JOURNAL OF VIROLOGY

CBP/p300-mediated acetylation of histone H3 on lysine 56

(2009) Chandrima Das et al.   NATURE

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

(2009) Jeanne Morinière et al.   NATURE

A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics

(2009) A. M. Quinn et al.   NUCLEIC ACIDS RESEARCH

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

Thermodynamic analysis of acetylation-dependent Pb1 bromodomain–histone H3 interactions

(2008) Martin Thompson et al.   ANALYTICAL BIOCHEMISTRY

Structural Basis and Binding Properties of the Second Bromodomain of Brd4 with Acetylated Histone Tails†‡

(2008) Ying Liu et al.   BIOCHEMISTRY

Bromodomain Protein Brd4 Regulates Human Immunodeficiency Virus Transcription through Phosphorylation of CDK9 at Threonine 29

(2008) M. Zhou et al.   JOURNAL OF VIROLOGY

The EBNA1 Protein of Epstein-Barr Virus Functionally Interacts with Brd4

(2008) A. Lin et al.   JOURNAL OF VIROLOGY

Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA

(2008) B. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Bromodomain 4 activation predicts breast cancer survival

(2008) N. P. S. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300

(2008) Lei Zeng et al.   STRUCTURE