Molecular modeling of the human serotonin1Areceptor: role of membrane cholesterol in ligand binding of the receptor

Making membrane proteins for structures: a trillion tiny tweaks

(2010) Monya Baker   NATURE METHODS

Mutant mouse models and antidepressant drug research: focus on serotonin and brain-derived neurotrophic factor

(2009) Alain M. Gardier   BEHAVIOURAL PHARMACOLOGY

G-protein-coupled receptor-focused drug discovery using a target class platform approach

(2009) Ralf Heilker et al.   DRUG DISCOVERY TODAY

Combining an Elastic Network With a Coarse-Grained Molecular Force Field: Structure, Dynamics, and Intermolecular Recognition

(2009) Xavier Periole et al.   Journal of Chemical Theory and Computation

Revisiting Automated G-Protein Coupled Receptor Modeling: The Benefit of Additional Template Structures for a Neurokinin-1 Receptor Model

(2009) Benny Kneissl et al.   JOURNAL OF MEDICINAL CHEMISTRY

Modern Homology Modeling of G-Protein Coupled Receptors: Which Structural Template to Use?

(2009) Juan Carlos Mobarec et al.   JOURNAL OF MEDICINAL CHEMISTRY

Membrane protein biophysics

(2009) Lesley Anson   NATURE

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

A Role for a Specific Cholesterol Interaction in Stabilizing the Apo Configuration of the Human A 2A Adenosine Receptor

(2009) Edward Lyman et al.   STRUCTURE

Signaling by the human serotonin1A receptor is impaired in cellular model of Smith–Lemli–Opitz Syndrome

(2008) Yamuna Devi Paila et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Are specific nonannular cholesterol binding sites present in G-protein coupled receptors?

(2008) Yamuna Devi Paila et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipid-mediated dimerization of β2-adrenergic receptor reveals important clues for cannabinoid receptors

(2008) E. Dainese et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The function of G-protein coupled receptors and membrane cholesterol: specific or general interaction?

(2008) Yamuna Devi Paila et al.   GLYCOCONJUGATE JOURNAL

The MARTINI Coarse-Grained Force Field: Extension to Proteins

(2008) Luca Monticelli et al.   Journal of Chemical Theory and Computation

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Structural and dynamic effects of cholesterol at preferred sites of interaction with rhodopsin identified from microsecond length molecular dynamics simulations

(2008) George Khelashvili et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE

A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor

(2008) Michael A. Hanson et al.   STRUCTURE