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Transfection microarray (TM) and the applications

Journal

MOLECULAR BIOSYSTEMS
Volume 5, Issue 5, Pages 444-449

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b821731a

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Funding

  1. Ministry of Economy, Trade and Industry (METI) of Japan
  2. New Energy and Industrial Technology Development Organization (NEDO)
  3. Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan
  4. National Institute of Advanced Industrial Science and Technology (AIST)
  5. Mechanical Social Systems Foundation

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Microarray transfection has been extensively studied for high-throughput functional analysis of mammalian cells. However, control of efficiency and reproducibility are the critical issues for practical use. By using solid-phase transfection accelerators and nano-scaffold, we provide a highly efficient and reproducible microarray-transfection device, transfection microarrayt. The device would be applied to the limited number of available primary cells and stem cells not only for large-scale functional analysis but also reporter-based time-lapse cellular event analysis.

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