Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis

DNA methylation imprinting marks and DNA methyltransferase expression in human spermatogenic cell stages

(2012) C. Joana Marques et al.   Epigenetics

ALCAPs induce mitochondrial apoptosis and activate DNA damage response by generating ROS and inhibiting topoisomerase I enzyme activity in K562 leukemia cell line

(2011) Nuray Bogurcu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Application of Delivery Systems for DNA Methyltransferase Inhibitors

(2011) Sue Ping Lim et al.   BIODRUGS

Enhancement of Carboplatin-Mediated Lung Cancer Cell Killing by Simultaneous Disruption of Glutathione and Thioredoxin Metabolism

(2011) M. A. Fath et al.   CLINICAL CANCER RESEARCH

DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer

(2011) Y. Kobayashi et al.   GENOME RESEARCH

Effects of genome architecture and epigenetic factors on susceptibility of promoter CpG islands to aberrant DNA methylation induction

(2011) Hideyuki Takeshima et al.   GENOMICS

Genetic and epigenetic changes of HPV16 in cervical cancer differentially regulate E6/E7 expression and associate with disease progression

(2011) Dipanjana Mazumder (Indra) et al.   GYNECOLOGIC ONCOLOGY

Epigenetic changes by zebularine leading to enhanced differentiation of human promyelocytic leukemia NB4 and KG1 cells

(2011) Jurate Savickiene et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

ZIC1 Is Downregulated through Promoter Hypermethylation, and Functions as a Tumor Suppressor Gene in Colorectal Cancer

(2011) Lihong Gan et al.   PLoS One

New Ways to Use DNA Methyltransferase Inhibitors for the Treatment of Myelodysplastic Syndrome

(2011) S. D. Gore   Hematology-American Society of Hematology Education Program

Overexpression of DNA Methyltransferases 1, 3a, and 3b Significantly Correlates With Retinoblastoma Tumorigenesis

(2010) Yi Qu et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism

(2010) Jayaraj Ravindran et al.   APOPTOSIS

General Transcription Factor Binding at CpG Islands in Normal Cells Correlates with Resistance to De novo DNA Methylation in Cancer Cells

(2010) C. Gebhard et al.   CANCER RESEARCH

DNA methyltransferase DNMT3b protein overexpression as a prognostic factor in patients with diffuse large B-cell lymphomas

(2010) Khaled Amara et al.   CANCER SCIENCE

The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients

(2010) Ruo-Kai Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation

(2010) Giovanni L Gravina et al.   Molecular Cancer

Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells

(2009) Madhavi Billam et al.   BREAST CANCER RESEARCH AND TREATMENT

Development of DNA Methyltransferase Inhibitors for the Treatment of Neoplastic Diseases

(2009) Tamer Fandy   CURRENT MEDICINAL CHEMISTRY

The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

(2009) C Flotho et al.   LEUKEMIA

5-Aza-2′-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1

(2009) Min Cui et al.   MEDICAL ONCOLOGY

Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2′-deoxycytidine and retinoic acid

(2009) A. Vivaldi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells

(2007) Shan Gao et al.   LEUKEMIA RESEARCH

Apoptosis in pyrogallol-treated Calu-6 cells is correlated with the changes of intracellular GSH levels rather than ROS levels

(2007) Yong Hwan Han et al.   LUNG CANCER

2,4-Dinitrophenol induces G1 phase arrest and apoptosis in human pulmonary adenocarcinoma Calu-6 cells

(2007) Yong Hwan Han et al.   TOXICOLOGY IN VITRO