ATF4 orchestrates a program of BH3-only protein expression in severe hypoxia

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

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Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation

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Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia

(2011) Tomasz Rzymski et al.   CELL CYCLE

Pancreatic cancers require autophagy for tumor growth

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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

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The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

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Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival

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The role of the Atg1/ULK1 complex in autophagy regulation

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Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4-CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA

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Autophagy and the Integrated Stress Response

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Regulation of autophagy by ATF4 in response to severe hypoxia

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Activation of PERK Signaling Attenuates Aβ-Mediated ER Stress

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The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

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The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib

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Autophagy Suppresses Tumorigenesis through Elimination of p62

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Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis

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PUMA- and Bax-induced autophagy contributes to apoptosis

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Hypoxia-induced Expression of Carbonic Anhydrase 9 Is Dependent on the Unfolded Protein Response

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

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Polyglutamine-Expanded Androgen Receptor Truncation Fragments Activate a Bax-Dependent Apoptotic Cascade Mediated by DP5/Hrk

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The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons

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ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

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Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3

(2009) Hilda Mujcic et al.   RADIOTHERAPY AND ONCOLOGY

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

(2008) M. L. Duennwald et al.   GENES & DEVELOPMENT

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-κB and ATF4

(2008) T Rzymski et al.   ONCOGENE

The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family

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Activating transcription factor 4

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