Article
Food Science & Technology
Zhiting Xu, Shuqi Diao, Jinyan Teng, Zitao Chen, Xueyan Feng, Xiaotian Cai, Xiaolong Yuan, Hao Zhang, Jiaqi Li, Zhe Zhang
Summary: The study focuses on breed identification through genetic markers genotyped from meat products, and highlights the importance of breed tag SNPs and machine learning methods in improving identification accuracy.
Article
Agriculture, Dairy & Animal Science
Shinichiro Ogawa, Natsumi Yazaki, Chika Ohnishi, Kazuo Ishii, Yoshinobu Uemoto, Masahiro Satoh
Summary: The study found that considering common litter environmental effects allows for more accurate estimation of genetic parameters for body measurement traits and meat production traits in pigs, while including maternal genetic effects in the model leads to larger standard errors in estimated genetic parameters.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2021)
Article
Food Science & Technology
Yufei Guo, Katharine Sharp, Harvey Blackburn, Brian Richert, Kara Stewart, Stacy M. S. Zuelly
Summary: This study compared the meat processing characteristics of different pig breeds and diets, and found that breed and diet had significant effects on the length, thickness, lean area, processing yield, color, and firmness of the pork.
Article
Plant Sciences
Nayoung Ro, Mesfin Haile, Bichsaem Kim, Gyu-Taek Cho, Jungro Lee, Yoon-Jung Lee, Do Yoon Hyun
Summary: This study established a core collection of eggplant genetic resources and identified SNPs associated with important agro-morphological traits. The findings are valuable for the selection and breeding programs of eggplant genetic resources.
Article
Genetics & Heredity
Alexander Krivoruchko, Andrey Likhovid, Anastasiya Kanibolotskaya, Tatiana Saprikina, Elena Safaryan, Olesya Yatsyk
Summary: In a group of Karachaevsky rams, a genome-wide association analysis was conducted to investigate the relationship between single nucleotide polymorphisms (SNPs) and meat production parameters. The study identified 12 SNPs that were significantly associated with live meat quality parameters. Additionally, 11 candidate genes were described, which may have an impact on sheep body parameters. These genes are involved in metabolic pathways related to cell differentiation, proliferation, and apoptosis, and are connected to the regulation of the gastrointestinal, immune, and nervous systems.
Article
Agriculture, Dairy & Animal Science
Mahboob Alam, Hyuk-Kee Chang, Seung-Soo Lee, Tae-Jeong Choi
Summary: The study investigated the genetic parameters of production and reproduction traits in Korean Duroc, Landrace, and Yorkshire pigs, revealing moderate to high heritability of production traits and low heritability of reproduction traits. Genetic correlations were found between certain traits, emphasizing the importance of careful breeding plans. The findings suggest potential for further improvement through selective breeding in Korean pig populations.
Article
Food Science & Technology
Andrea Ianni, Francesca Bennato, Camillo Martino, Maurizio Odoardi, Agostino Sacchetti, Giuseppe Martino
Summary: This study characterized the qualitative properties of commercial meat obtained from the Nero d'Abruzzo pig breed. The results showed that the Nero d'Abruzzo meat had higher fat content, higher concentration of alpha-linolenic acid, and higher Coenzyme Q10 content compared to meat from hybrid pigs. The Nero d'Abruzzo meat also exhibited better oxidative stability and reduced accumulation of hexanal.
Article
Agriculture, Dairy & Animal Science
Yang Li, Lei Pu, Liangyu Shi, Hongding Gao, Pengfei Zhang, Lixian Wang, Fuping Zhao
Summary: Number of teats is crucial for lactating sows. Genome-wide association studies identified significant SNPs related to teat number traits, providing new insights into the genetic mechanism of these traits in pigs.
Article
Agronomy
Yutian Gao, Xiangru Xu, Jingjing Jin, Shuonan Duan, Wenchao Zhen, Chaojie Xie, Jun Ma
Summary: This study identified 189 SNPs associated with six grain morphology traits in Chinese wheat germplasm, with some SNPs continuously detected across three experiments. Genes on chromosome 5A and 2D are suggested to play crucial roles in determining seed size and weight. Future experiments will further characterize the function of these genes in grain development.
Article
Biochemistry & Molecular Biology
Seong-Hoon Kim, Rupesh Tayade, Byeong-Hee Kang, Bum-Soo Hahn, Bo-Keun Ha, Yoon-Ha Kim
Summary: This study conducted a genome-wide association study (GWAS) on 357 soybean landraces to analyze root traits. It identified 112 significant SNP loci and 55 putative candidate genes. These findings suggest that the combined approach of SNP array and GWAS can be used to understand the genetic basis of soybean root traits and improve soybean breeding.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agriculture, Dairy & Animal Science
H. Wilmot, G. Glorieux, X. Hubin, N. Gengler
Summary: A genomic breed assignment test successfully classified meat samples of Dual-Purpose Blue and Beef Belgian Blue into their breed of origin, demonstrating the potential for routine use in certifying the breed of meat products.
Article
Agriculture, Dairy & Animal Science
H. Wilmot, G. Glorieux, X. Hubin, N. Gengler
Summary: The study aimed to differentiate meat of the endangered breed Dual-Purpose Blue from meat of the widely-used Beef Belgian Blue by using a genomic breed assignment test. The test successfully classified all meat samples into their respective breeds of origin.
Article
Veterinary Sciences
Shenping Zhou, Rongrong Ding, Zhanwei Zhuang, Haiyu Zeng, Shuxian Wen, Donglin Ruan, Jie Wu, Yibin Qiu, Enqin Zheng, Gengyuan Cai, Jie Yang, Zhenfang Wu, Ming Yang
Summary: In this study, single-trait and multi-trait genome-wide association studies were performed to investigate the genetics of chest circumference, abdominal circumference, and waist circumference in Duroc pigs. A novel quantitative trait locus on Sus scrofa chromosome one was identified, and 21 significant SNPs associated with the three conformation traits were identified through multi-trait GWAS. Furthermore, three candidate genes related to sphingolipid metabolism and lysosome pathways were discovered.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Genetics & Heredity
Qun Lan, Qiuchun Deng, Shijin Qi, Yuebo Zhang, Zhi Li, Shishu Yin, Yulian Li, Hong Tan, Maisheng Wu, Yulong Yin, Jun He, Mei Liu
Summary: With the increasing popularity of genomic sequencing, breeders are paying attention to identifying molecular markers and quantitative trait loci for improving the body size and reproductive traits of pig breeds. However, the relationship between phenotypes and genetic architecture in the Shaziling pig, an indigenous breed in China, is largely unknown. In this study, a total of 190 Shaziling samples were genotyped and analyzed for genetic associations with body measurement and reproduction traits. 31 SNPs associated with body length, chest circumference, number of healthy births, and number of stillborns were found, and 18 functional genes related to skeletal morphogenesis, chondrogenesis, obesity, and embryonic and fetal development were identified.
Article
Agriculture, Dairy & Animal Science
Chen Wei, Haonan Zeng, Zhanming Zhong, Xiaodian Cai, Jingyan Teng, Yuqiang Liu, Yunxiang Zhao, Xibo Wu, Jiaqi Li, Zhe Zhang
Summary: This study identified potential candidate genes affecting growth and carcass traits in pigs using whole-genome and transcriptome sequencing technologies. By analyzing the sequencing data of 4154 Duroc pigs, 80 significant genetic factors related to growth and carcass traits were discovered. These findings contribute to improving meat production and quality selection in pigs.
Correction
Cardiac & Cardiovascular Systems
Vincenzo Russo, Alfredo Caturano, Federico Guerra, Federico Migliore, Giuseppe Mascia, Andrea Rossi, Martina Nesti, Vincenzo Ezio Santobuono, Emilio Attena, Gianfranco Tola, Luigi Sciarra, Giulio Conte, Alessandro Paoletti Perini, Pietro Francia, Gregory Dendramis, Zefferino Palama, Stefano Albani, Andrea Ottonelli Ghidini, Leonardo Calo, Antonio D'Onofrio, Enrico Baldi
Article
Cardiac & Cardiovascular Systems
Vincenzo Russo, Alfredo Caturano, Federico Guerra, Federico Migliore, Giuseppe Mascia, Andrea Rossi, Martina Nesti, Vincenzo Ezio Santobuono, Emilio Attena, Gianfranco Tola, Luigi Sciarra, Giulio Conte, Alessandro Paoletti Perini, Pietro Francia, Gregory Dendramis, Zefferino Palama, Stefano Albani, Andrea Ottonelli Ghidini, Leonardo Calo, Antonio D'Onofrio, Enrico Baldi
Summary: This study compares device-related complications, infections, and inappropriate therapies between drug-induced type 1 Brugada Syndrome patients with transvenous-ICD (TV-ICD) and subcutaneous-ICD (S-ICD). The results show that there were no significant differences between S-ICD and TV-ICD in terms of inappropriate ICD therapies, device-related complications, and infections. However, the S-ICD group had a trend towards reduced lead-related complications.
Article
Biochemistry & Molecular Biology
Simona Daniele, Simona Saporiti, Stefano Capaldi, Deborah Pietrobono, Lara Russo, Uliano Guerrini, Tommaso Laurenzi, Elham Ataie Kachoie, Luca Palazzolo, Vincenzo Russo, Maria Pia Abbracchio, Ivano Eberini, Maria Letizia Trincavelli
Summary: GPR17, a key regulator of myelination, is activated by endogenous ligands and pro-inflammatory molecules. This study investigates the structural and functional interactions between GPR17 and chemokine receptors CXCR2 and CXCR4. The results show that these receptors can form heterodimers and modulate intracellular cAMP levels. This cross-talk between receptors could impact the neuroinflammatory environment associated with demyelinating events.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Medicine, General & Internal
Anna Lombardi, Mariarosaria De Luca, Dario Fabiani, Francesco Sabatella, Carmen Del Giudice, Adriano Caputo, Luigi Cante, Michele Gambardella, Stefano Palermi, Rita Tavarozzi, Vincenzo Russo, Antonello D'Andrea
Summary: SARS-CoV-2 rapidly spread globally, causing the costly and deadly COVID-19 pandemic. Pulmonary manifestations are common in this syndrome, along with frequent cardiovascular complications. Ultrasound evaluations, particularly POCUS protocols, are crucial in diagnosing, monitoring, and predicting the prognosis of COVID-19 patients, especially in intensive care units.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Andreina Carbone, Roberta Bottino, Antonello D'Andrea, Vincenzo Russo
Summary: Currently, direct oral anticoagulants (DOACs) are the first-line anticoagulant strategy for non-valvular atrial fibrillation (NVAF) patients, showing equal efficacy and greater safety compared to warfarin. However, the results of DOAC trials cannot be extrapolated to specific populations such as obese, elderly, frail, and cancer patients, which are common in clinical practice. Additionally, the evidence for DOAC use in patients with bioprosthetic heart valves is limited and controversial. This review aims to clarify the best anticoagulant strategy for these special and understudied subpopulations.
Article
Agriculture, Dairy & Animal Science
Samuele Bovo, Anisa Ribani, Valerio Joe Utzeri, Valeria Taurisano, Gianmaria Bertarini, Luca Fontanesi
Summary: In this study, whole genome sequencing data from five canary lines or populations were analyzed to identify candidate genes associated with pigmentation variability in canary breeds and varieties. The study revealed genes involved in carotenoid-derived pigmentation variants and melanogenesis-related genes, with putative causative mutations identified in the MLPH gene. Additionally, other signatures of selection were found that may explain phenotypic differences between canary populations.
Letter
Food Science & Technology
Luca Fontanesi, Valeria Taurisano, Anisa Ribani, Valerio Joe Utzeri
Review
Cardiac & Cardiovascular Systems
Michele Iavarone, Anna Rago, Riccardo Molinari, Antonello D'Andrea, Martina Nesti, Saverio Muscoli, Giuseppe Mascia, Vincenzo Russo
Summary: Sudden cardiac death (SCD) is a leading cause of cardiovascular death, and identifying high-risk patients for primary prevention is crucial. Noninvasive arrhythmic risk indexes are available but their effectiveness is debated. Programmed ventricular stimulation (PVS) is an invasive approach historically used for SCD risk stratification and is included in international guidelines. This review aims to summarize available data regarding the role of PVS for SCD risk stratification in different clinical settings.
REVIEWS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Vincenzo Russo, Michele Ciabatti, Michele Brunacci, Gregory Dendramis, Vincenzo Santobuono, Gianfranco Tola, Giuseppe Picciolo, Lucciola Maria Teresa, Antonello D'Andrea, Martina Nesti
Summary: The subcutaneous implantable cardioverter-defibrillator (S-ICD) is a well-established therapy for preventing sudden cardiac death and serves as an alternative to transvenous implantable cardioverter-defibrillator systems for selected patients. Numerous observational studies have examined the clinical performance of S-ICD in different patient subgroups. This review aims to outline the advantages and disadvantages of S-ICD, particularly in special populations and various clinical settings.
EXPERT REVIEW OF CARDIOVASCULAR THERAPY
(2023)
Article
Agriculture, Dairy & Animal Science
Mohamad Ballan, Samuele Bovo, Francesca Bertolini, Giuseppina Schiavo, Michele Schiavitto, Riccardo Negrini, Luca Fontanesi
Summary: In this study, genotyping and analysis revealed the genetic relationship between exterior traits and rabbit breeds. It was found that breeds with similar phenotypic traits shared common ancestries and specific genes associated with coat color and body size were identified. This study provides insights into the genetic events that led to the formation of rabbit breeds and the genetic mechanisms behind their phenotypic variability.
JOURNAL OF ANIMAL BREEDING AND GENETICS
(2023)
Article
Psychology, Multidisciplinary
Vincenzo Russo, Marco Bilucaglia, Chiara Casiraghi, Simone Chiarelli, Martina Columbano, Alessandro Fici, Fiamma Rivetti, Cristina Rossi, Riccardo Valesi, Margherita Zito
Summary: This paper presents an innovative research project that explores the emotional factors influencing decision-making in response to infomercials using cutting-edge consumer neuroscience techniques. The study identifies various variables, including seller characteristics and neurophysiological responses, that significantly impact the effectiveness of infomercials in generating Call-to-Action, Purchase Intention, and likability. The findings emphasize the importance of considering both seller attributes and consumers' neurophysiological responses in understanding and predicting their behaviors towards marketing stimuli.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Alfredo Caturano, Margherita D'Angelo, Andrea Mormone, Vincenzo Russo, Maria Pina Mollica, Teresa Salvatore, Raffaele Galiero, Luca Rinaldi, Erica Vetrano, Raffaele Marfella, Marcellino Monda, Antonio Giordano, Ferdinando Carlo Sasso
Summary: Oxidative stress plays a critical role in the development and progression of diabetes and its associated complications. The imbalance between reactive oxygen species (ROS) production and the body's antioxidant defense mechanisms leads to cellular damage and dysfunction. By understanding and addressing oxidative stress, it may be possible to alleviate the burden of diabetes and improve patient outcomes.
CURRENT ISSUES IN MOLECULAR BIOLOGY
(2023)
Review
Medicine, General & Internal
Anna Rago, Ciro Pirozzi, Antonello D'Andrea, Pierpaolo Di Micco, Andrea Antonio Papa, Antonio D'Onofrio, Paolo Golino, Gerardo Nigro, Vincenzo Russo
Summary: This review evaluates the gender-related differences in cardioembolic risk and response to anticoagulants in atrial fibrillation patients. Non-vitamin K oral anticoagulants (NOACs) are the gold standard for thromboembolic risk prevention in non-valvular atrial fibrillation patients. In comparison to men, the use of NOACs in women with atrial fibrillation is associated with a lower risk of intracranial bleeding, major bleeding, and all-cause mortality.
MEDICINA-LITHUANIA
(2023)
Review
Genetics & Heredity
Alfredo Mauriello, Antonia Ascrizzi, Riccardo Molinari, Luigi Falco, Alfredo Caturano, Antonello D'Andrea, Vincenzo Russo
Summary: Pharmacogenomics plays an important role in personalized medicine, especially in the field of cardiovascular drug therapy. Genotype-guided approach improves the effectiveness of antiplatelet therapy, while various genetic polymorphisms affect the efficacy of anticoagulants and statin drugs. Pharmacogenomics has the potential to guide new drug therapies for cardiovascular diseases.
Meeting Abstract
Surgery
D. Khan, K. Tariq, K. Lee, E. Dyson, V. Russo, L. Watkins, A. Russo
BRITISH JOURNAL OF SURGERY
(2023)