4.5 Article

Molecular regulation of mast cell development and maturation

Journal

MOLECULAR BIOLOGY REPORTS
Volume 37, Issue 4, Pages 1993-2001

Publisher

SPRINGER
DOI: 10.1007/s11033-009-9650-z

Keywords

Mast cells; Mast cell-committed progenitors; SCF; Allergy

Funding

  1. Natural Science Foundation of China [30871273]
  2. Natural Science Foundation of Guangdong Province

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Mast cells play a crucial role in the pathogenesis of allergic diseases. In recent years, tremendous progresses have been made in studies of mast cell origination, migration, proliferation, maturation and survival, and the cytokines regulating these activities. These advances have significantly improved our understandings to mast cell biology and to the molecular mechanisms of mast cells in the pathogenesis of allergic diseases.

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