Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway

Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1

(2015) Maria Giovanna Francipane et al.   Oncotarget

CHAC1/MGC4504 Is a Novel Proapoptotic Component of the Unfolded Protein Response, Downstream of the ATF4-ATF3-CHOP Cascade

(2014) I. N. Mungrue et al.   JOURNAL OF IMMUNOLOGY

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine

(2014) Julian Heuberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids

(2013) Hongliang Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

NFAT5 represses canonical Wnt signaling via inhibition of β -catenin acetylation and participates in regulating intestinal cell differentiation

(2013) Q Wang et al.   Cell Death & Disease

Pharmacological Control of Autophagy: Therapeutic Perspectives in Inflammatory Bowel Disease and Colorectal Cancer

(2012) Sofia Garcia-Maurino et al.   CURRENT PHARMACEUTICAL DESIGN

Intestinal Epithelial Toll-Like Receptor 4 Regulates Goblet Cell Development and Is Required for Necrotizing Enterocolitis in Mice

(2012) Chhinder P. Sodhi et al.   GASTROENTEROLOGY

Innate immune dysfunction in inflammatory bowel disease

(2012) M. Gersemann et al.   JOURNAL OF INTERNAL MEDICINE

Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells

(2012) Yuning Zhou et al.   MOLECULAR BIOLOGY OF THE CELL

The Stress-Response Gene redd1 Regulates Dorsoventral Patterning by Antagonizing Wnt/β-catenin Activity in Zebrafish

(2012) Qiang Feng et al.   PLoS One

Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation

(2012) Anthony B. Mak et al.   Cell Reports

Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells

(2011) Min Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Regulation of self-renewal and differentiation by the intestinal stem cell niche

(2011) Trevor M. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Notch: Architect, Landscaper, and Guardian of the Intestine

(2011) Marc Vooijs et al.   GASTROENTEROLOGY

Nuclear Factor of Activated T Cells (NFAT) Proteins Repress Canonical Wnt Signaling via Its Interaction with Dishevelled (Dvl) Protein and Participate in Regulating Neural Progenitor Cell Proliferation and Differentiation

(2011) Tao Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAIL up-regulation must be accompanied by a reciprocal PKCε down-regulation during differentiation of colonic epithelial cell: Implications for colorectal cancer cell differentiation

(2011) Giuliana Gobbi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TXNIP potentiates Redd1-induced mTOR suppression through stabilization of Redd1

(2011) H-O Jin et al.   ONCOGENE

NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer

(2010) S. S. Sikandar et al.   CANCER RESEARCH

Role of NFAT5 in Inflammatory Disorders Associated with Osmotic Stress

(2010) Wolfgang Neuhofer   CURRENT GENOMICS

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

(2010) Markus Mair et al.   GASTROENTEROLOGY

CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype

(2010) R. Barros et al.   GUT

New roles for Notch in tuberous sclerosis

(2010) Warren S. Pear   JOURNAL OF CLINICAL INVESTIGATION

Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade

(2010) Jianhui Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

NFAT5 Regulates T Lymphocyte Homeostasis and CD24-Dependent T Cell Expansion under Pathologic Hypernatremia

(2010) R. Berga-Bolanos et al.   JOURNAL OF IMMUNOLOGY

Nuclear factor of activated T cells (NFAT) signaling regulates PTEN expression and intestinal cell differentiation

(2010) Qingding Wang et al.   MOLECULAR BIOLOGY OF THE CELL

A Novel Mouse Model of Inflammatory Bowel Disease Links Mammalian Target of Rapamycin-Dependent Hyperproliferation of Colonic Epithelium to Inflammation-Associated Tumorigenesis

(2009) Lin Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

Signal Transducer and Activator of Transcription 3 (STAT3) Mediates Amino Acid Inhibition of Insulin Signaling through Serine 727 Phosphorylation

(2009) Jeong-Ho Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcineurin/NFAT Signaling Is Required for Neuregulin-Regulated Schwann Cell Differentiation

(2009) S.-C. Kao et al.   SCIENCE

Hypoxia regulates TSC1/2 mTOR signaling and tumor suppression through REDD1-mediated 14 3 3 shuttling

(2008) M. P. DeYoung et al.   GENES & DEVELOPMENT