Modularity and predictability in cell signaling and decision making

Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development

(2014) Sean C. Bendall et al.   CELL

Encoding of Temporal Signals by the TGF-β Pathway and Implications for Embryonic Patterning

(2014) Benoit Sorre et al.   DEVELOPMENTAL CELL

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

(2014) D. A. Jaitin et al.   SCIENCE

RETRACTED: (p)ppGpp Controls Bacterial Persistence by Stochastic Induction of Toxin-Antitoxin Activity

(2013) Etienne Maisonneuve et al.   CELL

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

(2013) Sabrina L. Spencer et al.   CELL

Nanog Heterogeneity: Tilting at Windmills?

(2013) Austin Smith   Cell Stem Cell

Feedforward Regulation Ensures Stability and Rapid Reversibility of a Cellular State

(2013) Andreas Doncic et al.   MOLECULAR CELL

The causes and consequences of genetic heterogeneity in cancer evolution

(2013) Rebecca A. Burrell et al.   NATURE

Pheromone-Induced Morphogenesis Improves Osmoadaptation Capacity by Activating the HOG MAPK Pathway

(2013) R. Baltanas et al.   Science Signaling

Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression

(2013) Christopher R. Brown et al.   PLOS BIOLOGY

Dynamics of TGF-  signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4

(2012) A. Warmflash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What Evidence Is There for the Homology of Protein-Protein Interactions?

(2012) Anna C. F. Lewis et al.   PLoS Computational Biology

Distinct Interactions Select and Maintain a Specific Cell Fate

(2011) Andreas Doncic et al.   MOLECULAR CELL

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum

(2011) S. C. Bendall et al.   SCIENCE

A general lack of compensation for gene dosage in yeast

(2010) Michael Springer et al.   Molecular Systems Biology

Variability in gene expression underlies incomplete penetrance

(2010) Arjun Raj et al.   NATURE

Single-Cell Analysis Reveals That Insulation Maintains Signaling Specificity Between Two Yeast MAPK Pathways with Common Components

(2010) J. C. Patterson et al.   Science Signaling

Evolution of Stochastic Switching Rates in Asymmetric Fitness Landscapes

(2009) Marcel Salathé et al.   GENETICS

Global Analysis of Cdk1 Substrate Phosphorylation Sites Provides Insights into Evolution

(2009) L. J. Holt et al.   SCIENCE

Robustness: mechanisms and consequences

(2009) Joanna Masel et al.   TRENDS IN GENETICS

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Nucleus-Specific and Cell Cycle-Regulated Degradation of Mitogen-Activated Protein Kinase Scaffold Protein Ste5 Contributes to the Control of Signaling Competence

(2008) L. S. Garrenton et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE

Positive feedback of G1 cyclins ensures coherent cell cycle entry

(2008) Jan M. Skotheim et al.   NATURE

A bistable Rb–E2F switch underlies the restriction point

(2008) Guang Yao et al.   NATURE CELL BIOLOGY

Transient-mediated fate determination in a transcriptional circuit of HIV

(2008) Leor S Weinberger et al.   NATURE GENETICS

Stochastic switching as a survival strategy in fluctuating environments

(2008) Murat Acar et al.   NATURE GENETICS

Information flow and optimization in transcriptional regulation

(2008) G. Tkacik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stochasticity and Cell Fate

(2008) R. Losick et al.   SCIENCE

Evolution of Eukaryotic Transcription Circuits

(2008) B. B. Tuch et al.   SCIENCE