Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis

A Trio–Rac1–Pak1 signalling axis drives invadopodia disassembly

(2014) Yasmin Moshfegh et al.   NATURE CELL BIOLOGY

The RhoGAP Domain of CYK-4 Has an Essential Role in RhoA Activation

(2012) Andy Loria et al.   CURRENT BIOLOGY

Rho GTPases in animal cell cytokinesis: An occupation by the one percent

(2012) Shawn N. Jordan et al.   Cytoskeleton

CYK4 inhibits Rac1-dependent PAK1 and ARHGEF7 effector pathways during cytokinesis

(2012) Ricardo Nunes Bastos et al.   JOURNAL OF CELL BIOLOGY

Tyrosine Phosphorylation of the Rho Guanine Nucleotide Exchange Factor Trio Regulates Netrin-1/DCC-Mediated Cortical Axon Outgrowth

(2012) J. DeGeer et al.   MOLECULAR AND CELLULAR BIOLOGY

The N-Terminal DH-PH Domain of Trio Induces Cell Spreading and Migration by Regulating Lamellipodia Dynamics in a Rac1-Dependent Fashion

(2012) Jos van Rijssel et al.   PLoS One

A Cell Active Chemical GEF Inhibitor Selectively Targets the Trio/RhoG/Rac1 Signaling Pathway

(2009) Nathalie Bouquier et al.   CHEMISTRY & BIOLOGY

Cytokinesis: mind the GAP

(2009) Pier Paolo D'Avino et al.   NATURE CELL BIOLOGY

Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation

(2009) Benjamin A. Wolfe et al.   PLOS BIOLOGY

CUX1 and E2F1 Regulate Coordinated Expression of the Mitotic Complex Genes Ect2, MgcRacGAP, and MKLP1 in S Phase

(2008) L. Seguin et al.   MOLECULAR AND CELLULAR BIOLOGY

Trio Mediates Netrin-1-Induced Rac1 Activation in Axon Outgrowth and Guidance

(2008) A. Briancon-Marjollet et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of Rac by the GAP Activity of Centralspindlin Is Essential for Cytokinesis

(2008) J. C. Canman et al.   SCIENCE