The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development

R-Ras is required for murine dendritic cell maturation and CD4+ T-cell priming

(2011) G. Singh et al.   BLOOD

Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation

(2011) Antonio Castro-Castro et al.   EMBO JOURNAL

T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis

(2011) Nuria Martínez-Martín et al.   IMMUNITY

Greater expression of TC21/R-ras2 in highly aggressive malignant skin cancer

(2011) Jang Hyun Lee et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

R-Ras and Rac GTPase Cross-talk Regulates Hematopoietic Progenitor Cell Migration, Homing, and Mobilization

(2011) Xun Shang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrated morphodynamic signalling of the mammary gland

(2011) Nikolce Gjorevski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen

(2011) A. M. Mendes-Pereira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

(2010) Matthias Drosten et al.   EMBO JOURNAL

Clinical significance of TC21 overexpression in oral cancer

(2010) Muzafar A. Macha et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Structural and Spatial Determinants Regulating TC21 Activation by RasGRF Family Nucleotide Exchange Factors

(2009) Fernando Calvo et al.   MOLECULAR BIOLOGY OF THE CELL

Essential function for the GTPase TC21 in homeostatic antigen receptor signaling

(2009) Pilar Delgado et al.   NATURE IMMUNOLOGY

A Polymorphism in the TC21 Promoter Associates with an Unfavorable Tamoxifen Treatment Outcome in Breast Cancer

(2008) M. Rokavec et al.   CANCER RESEARCH

Lentiviral Transduction of Mammary Stem Cells for Analysis of Gene Function during Development and Cancer

(2008) Bryan E. Welm et al.   Cell Stem Cell