Origin of Robustness in Generating Drug-Resistant Malaria Parasites

Direct evidence for the adaptive role of copy number variation on antifolate susceptibility inPlasmodium falciparum

(2013) Adina Heinberg et al.   MOLECULAR MICROBIOLOGY

Mapping ‘partially resistant’, ‘fully resistant’, and ‘super resistant’ malaria

(2013) Inbarani Naidoo et al.   TRENDS IN PARASITOLOGY

Malaria Burden and Artemisinin Resistance in the Mobile and Migrant Population on the Thai–Myanmar Border, 1999–2011: An Observational Study

(2013) Verena I. Carrara et al.   PLOS MEDICINE

Stability-mediated epistasis constrains the evolution of an influenza protein

(2013) Lizhi Ian Gong et al.   eLife

Counter Perspective: Artemisinin Resistance: Facts, Fears, and Fables

(2012) Nicholas J. White   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Global malaria mortality between 1980 and 2010: a systematic analysis

(2012) Christopher JL Murray et al.   LANCET

The global pipeline of new medicines for the control and elimination of malaria

(2012) Melinda P Anthony et al.   MALARIA JOURNAL

A framework for assessing the risk of resistance for anti-malarials in development

(2012) Xavier C Ding et al.   MALARIA JOURNAL

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

(2012) Magnus Manske et al.   NATURE

Identifying apicoplast-targeting antimalarials using high-throughput compatible approaches

(2011) Eric H. Ekland et al.   FASEB JOURNAL

Evolutionary paths to antibiotic resistance under dynamically sustained drug selection

(2011) Erdal Toprak et al.   NATURE GENETICS

Fitness Trade-Offs in the Evolution of Dihydrofolate Reductase and Drug Resistance in Plasmodium falciparum

(2011) Marna S. Costanzo et al.   PLoS One

Co-expression of the Plasmodium falciparum molecular chaperone, PfHsp70, improves the heterologous production of the antimalarial drug target GTP cyclohydrolase I, PfGCHI

(2011) Linda L. Stephens et al.   PROTEIN EXPRESSION AND PURIFICATION

Second-Order Selection for Evolvability in a Large Escherichia coli Population

(2011) R. J. Woods et al.   SCIENCE

"Snakes and Ladders" of drug resistance evolution

(2011) Thanat Chookajorn et al.   Virulence

Compensation of Fitness Costs and Reversibility of Antibiotic Resistance Mutations

(2010) P. Schulz zur Wiesch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Heat shock protein 90: a capacitor or a mutator?

(2010) Ritwick Sawarkar et al.   JOURNAL OF BIOSCIENCES

Compensatory Mutations Restore Fitness during the Evolution of Dihydrofolate Reductase

(2010) K. M. Brown et al.   MOLECULAR BIOLOGY AND EVOLUTION

Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons

(2010) Valeria Specchia et al.   NATURE

The Selection Landscape of Malaria Parasites

(2010) M. J. Mackinnon et al.   SCIENCE

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

Temporal Constraints on the Incorporation of Regulatory Mutants in Evolutionary Pathways

(2009) K. M. Brown et al.   MOLECULAR BIOLOGY AND EVOLUTION

Stepwise acquisition of pyrimethamine resistance in the malaria parasite

(2009) E. R. Lozovsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robustness: mechanisms and consequences

(2009) Joanna Masel et al.   TRENDS IN GENETICS

A regulatable transgene expression system for cultured Plasmodium falciparum parasites

(2008) Christian Epp et al.   MALARIA JOURNAL

Antifolate resistance in Africa and the 164-dollar question

(2008) John E. Hyde   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Adaptive Copy Number Evolution in Malaria Parasites

(2008) Shalini Nair et al.   PLoS Genetics