Novel Functional Complexity of Polycystin-1 by GPS Cleavage In Vivo: Role in Polycystic Kidney Disease

Progressive development of polycystic kidney disease in the mouse model expressing Pkd1 extracellular domain

(2013) Almira Kurbegovic et al.   HUMAN MOLECULAR GENETICS

Type of PKD1 Mutation Influences Renal Outcome in ADPKD

(2013) E. Cornec-Le Gall et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Matching structure with function: the GAIN domain of Adhesion-GPCR and PKD1-like proteins

(2013) Simone Prömel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors

(2012) Simone Prömel et al.   Cell Reports

LPA Receptor Heterodimerizes with CD97 to Amplify LPA-Initiated RHO-Dependent Signaling and Invasion in Prostate Cancer Cells

(2011) Y. Ward et al.   CANCER RESEARCH

The N Terminus of the Adhesion G Protein-coupled Receptor GPR56 Controls Receptor Signaling Activity

(2011) Kevin J. Paavola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Golgi Glycosylation

(2011) P. Stanley   Cold Spring Harbor Perspectives in Biology

GPS autoproteolysis is required for CD97 to up-regulate the expression of N-cadherin that promotes homotypic cell-cell aggregation

(2010) Cheng-Chih Hsiao et al.   FEBS LETTERS

Pkd1 transgenic mice: adult model of polycystic kidney disease with extrarenal and renal phenotypes

(2010) Almira Kurbegovic et al.   HUMAN MOLECULAR GENETICS

Polycystin-1 Surface Localization Is Stimulated by Polycystin-2 and Cleavage at the G Protein-coupled Receptor Proteolytic Site

(2010) Hannah C. Chapin et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of a Polycystin-1 Cleavage Product, P100, That Regulates Store Operated Ca2+ Entry through Interactions with STIM1

(2010) Owen M. Woodward et al.   PLoS One

Vasculostatin Inhibits Intracranial Glioma Growth and Negatively Regulates In vivo Angiogenesis through a CD36-Dependent Mechanism

(2009) B. Kaur et al.   CANCER RESEARCH

C-myc as a modulator of renal stem/progenitor cell population

(2009) Martin Couillard et al.   DEVELOPMENTAL DYNAMICS

Glomerular and proximal tubule cysts as early manifestations of Pkd1 deletion

(2009) Ali K. Ahrabi et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A Novel Mouse Model Reveals that Polycystin-1 Deficiency in Ependyma and Choroid Plexus Results in Dysfunctional Cilia and Hydrocephalus

(2009) Claas Wodarczyk et al.   PLoS One