Screening with a Novel Cell-Based Assay for TAZ Activators Identifies a Compound That Enhances Myogenesis in C2C12 Cells and Facilitates Muscle Repair in a Muscle Injury Model

New horizons in the pathogenesis, diagnosis and management of sarcopenia

(2013) A. A. Sayer et al.   AGE AND AGEING

Glucocorticoid-induced skeletal muscle atrophy

(2013) O. Schakman et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of Hippo Signaling in Cancer Stem Cells

(2013) Jin Hao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Overexpression of Hippo pathway effector TAZ in tongue squamous cell carcinoma: correlation with clinicopathological features and patients' prognosis

(2013) Zicheng Wei et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

TAZ Expression as a Prognostic Indicator in Colorectal Cancer

(2013) Hiu-Fung Yuen et al.   PLoS One

Constitutive Expression of Yes-Associated Protein (Yap) in Adult Skeletal Muscle Fibres Induces Muscle Atrophy and Myopathy

(2013) Robert N. Judson et al.   PLoS One

Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells

(2013) Lijuan Wang et al.   PLoS One

Role of TAZ as Mediator of Wnt Signaling

(2012) Luca Azzolin et al.   CELL

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling

(2012) Masamichi Imajo et al.   EMBO JOURNAL

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

(2012) Wanjin Hong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

TAZ is required for the osteogenic and anti-adipogenic activities of kaempferol

(2011) Mi Ran Byun et al.   BONE

TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ

(2011) EJ Jang et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Transcription factor TEAD4 regulates expression of Myogenin and the unfolded protein response genes during C2C12 cell differentiation

(2011) A Benhaddou et al.   CELL DEATH AND DIFFERENTIATION

The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma

(2011) K. P. L. Bhat et al.   GENES & DEVELOPMENT

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

(2011) B. Zhao et al.   GENES & DEVELOPMENT

Mammalian Hippo pathway: from development to cancer and beyond

(2011) Y. Bao et al.   JOURNAL OF BIOCHEMISTRY

A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription

(2011) Y. Bao et al.   JOURNAL OF BIOCHEMISTRY

Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin

(2011) Siew Wee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Marking the tempo for myogenesis: Pax7 and the regulation of muscle stem cell fate decisions

(2011) Hugo C. Olguín et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Satellite cells, the engines of muscle repair

(2011) Yu Xin Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TAZ is a novel oncogene in non-small cell lung cancer

(2011) Z Zhou et al.   ONCOGENE

Yap is a novel regulator of C2C12 myogenesis

(2010) Kevin I. Watt et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

(2010) Tsutomu Oka et al.   BIOCHEMICAL JOURNAL

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

The Hippo Signaling Pathway in Development and Cancer

(2010) Duojia Pan   DEVELOPMENTAL CELL

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

TAZ/WWTR1 is overexpressed in papillary thyroid carcinoma

(2010) Tiziana de Cristofaro et al.   EUROPEAN JOURNAL OF CANCER

TAZ as a novel enhancer of MyoD-mediated myogenic differentiation

(2010) Hana Jeong et al.   FASEB JOURNAL

Novel insights into the regulation of skeletal muscle protein synthesis as revealed by a new nonradioactive in vivo technique

(2010) Craig A. Goodman et al.   FASEB JOURNAL

TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner

(2010) Eline Remue et al.   FEBS LETTERS

WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ

(2010) S W Chan et al.   ONCOGENE

YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human diseaseThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Kainan Wang et al.   Biochemistry and Cell Biology

Roles of mammalian sterile 20-like kinase 2-dependent phosphorylations of Mps one binder 1B in the activation of nuclear Dbf2-related kinases

(2009) Yijun Bao et al.   GENES TO CELLS

TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation

(2009) Siew Wee Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

(2009) Heng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hippo Pathway-Dependent and -Independent Roles of RASSF6

(2009) M. Ikeda et al.   Science Signaling

A Role for TAZ in Migration, Invasion, and Tumorigenesis of Breast Cancer Cells

(2008) S. W. Chan et al.   CANCER RESEARCH

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

(2008) M. Ota et al.   DEVELOPMENT

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

(2008) Xaralabos Varelas et al.   NATURE CELL BIOLOGY

Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1

(2008) S Hirabayashi et al.   ONCOGENE