Activation of p53 Transcriptional Activity by SMRT: a Histone Deacetylase 3-Independent Function of a Transcriptional Corepressor

INPP4B: the New Kid on the PI3K Block

(2015) Irina U. Agoulnik et al.   Oncotarget

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo

(2013) Seo-Hee You et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Co-Repressor SMRT Delays DNA Damage-Induced Caspase Activation by Repressing Pro-Apoptotic Genes and Modulating the Dynamics of Checkpoint Kinase 2 Activation

(2013) Claudio Scafoglio et al.   PLoS One

Inositol Polyphosphate Multikinase Is a Coactivator of p53-Mediated Transcription and Cell Death

(2013) R. Xu et al.   Science Signaling

Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence

(2012) Carolyn L. Smith et al.   BREAST CANCER RESEARCH AND TREATMENT

Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis

(2012) F Nikulenkov et al.   CELL DEATH AND DIFFERENTIATION

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

(2012) Peter J. Watson et al.   NATURE

ERK1/2 Signaling Plays an Important Role in Topoisomerase II Poison-Induced G2/M Checkpoint Activation

(2012) Ryan H. Kolb et al.   PLoS One

The p53 response element and transcriptional repression

(2011) Bei Wang et al.   CELL CYCLE

Nuclear hormone receptor co-repressors: Structure and function

(2011) Peter J. Watson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

(2011) Jasmeen Oberoi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Inositol Pyrophosphates as Mammalian Cell Signals

(2011) A. Chakraborty et al.   Science Signaling

To repress or not to repress: This is the guardian's question

(2011) John L. Rinn et al.   TRENDS IN CELL BIOLOGY

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Cooperative Activation of Cyclin D1 and Progesterone Receptor Gene Expression by the SRC-3 Coactivator and SMRT Corepressor

(2010) Sudipan Karmakar et al.   MOLECULAR ENDOCRINOLOGY

Deconstructing repression: evolving models of co-repressor action

(2010) Valentina Perissi et al.   NATURE REVIEWS GENETICS

Genomic instability — an evolving hallmark of cancer

(2010) Simona Negrini et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

p53 post-translational modification: deregulated in tumorigenesis

(2010) Chao Dai et al.   TRENDS IN MOLECULAR MEDICINE

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

p53-cofactor JMY is a multifunctional actin nucleation factor

(2009) J. Bradley Zuchero et al.   NATURE CELL BIOLOGY

Disruption of estrogen receptor α-p53 interaction in breast tumors: a novel mechanism underlying the anti-tumor effect of radiation therapy

(2008) Wensheng Liu et al.   BREAST CANCER RESEARCH AND TREATMENT

Unique Roles of p160 Coactivators for Regulation of Breast Cancer Cell Proliferation and Estrogen Receptor-α Transcriptional Activity

(2008) Sudipan Karmakar et al.   ENDOCRINOLOGY

HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21

(2008) Andrew J. Wilson et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY