NCoR1 and SMRT Play Unique Roles in Thyroid Hormone ActionIn Vivo

Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TRβ1-governed pathway

(2014) Inna Astapova et al.   JOURNAL OF CLINICAL INVESTIGATION

Thyroid Hormone Signaling In Vivo Requires a Balance between Coactivators and Corepressors

(2014) K. R. Vella et al.   MOLECULAR AND CELLULAR BIOLOGY

Novel Mechanism of PositiveversusNegative Regulation by Thyroid Hormone Receptor β1 (TRβ1) Identified by Genome-wide Profiling of Binding Sites in Mouse Liver

(2013) Preeti Ramadoss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deacetylase-Independent Function of HDAC3 in Transcription and Metabolism Requires Nuclear Receptor Corepressor

(2013) Zheng Sun et al.   MOLECULAR CELL

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo

(2013) Seo-Hee You et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Rescue of a primary myelofibrosis model by retinoid-antagonist therapy

(2013) S.-H. Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The in vivo role of nuclear receptor corepressors in thyroid hormone action

(2012) Inna Astapova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Thyroid Axis Is Regulated by NCoR1 via Its Actions in the Pituitary

(2012) Ricardo H. Costa-e-Sousa et al.   ENDOCRINOLOGY

Regulated Clearance of Histone Deacetylase 3 Protects Independent Formation of Nuclear Receptor Corepressor Complexes

(2012) Chun Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

(2012) Fadila Benhamed et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

(2012) Mark A. Herman et al.   NATURE

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

(2012) Zheng Sun et al.   NATURE MEDICINE

Metabolic Health and Nuclear-Receptor Sensitivity

(2012) Anthony N. Hollenberg   NEW ENGLAND JOURNAL OF MEDICINE

Cytochrome P450s in the Regulation of Cellular Retinoic Acid Metabolism

(2011) A. Catharine Ross et al.   Annual Review of Nutrition

NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function

(2011) Hiroyasu Yamamoto et al.   CELL

Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity

(2011) Pingping Li et al.   CELL

NPY and MC4R Signaling Regulate Thyroid Hormone Levels during Fasting through Both Central and Peripheral Pathways

(2011) Kristen R. Vella et al.   Cell Metabolism

The Nuclear Receptor Corepressor (NCoR) Controls Thyroid Hormone Sensitivity and the Set Point of the Hypothalamic-Pituitary-Thyroid Axis

(2011) Inna Astapova et al.   MOLECULAR ENDOCRINOLOGY

Thyroid hormone receptor repression is linked to type I pneumocyte–associated respiratory distress syndrome

(2011) Liming Pei et al.   NATURE MEDICINE

Nuclear Receptor Corepressor SMRT Regulates Mitochondrial Oxidative Metabolism and Mediates Aging-Related Metabolic Deterioration

(2010) Shannon M. Reilly et al.   Cell Metabolism

Molecular Aspects of Thyroid Hormone Actions

(2010) Sheue-Yann Cheng et al.   ENDOCRINE REVIEWS

Thyroid Hormone Receptor β (TRβ) and Liver X Receptor (LXR) Regulate Carbohydrate-response Element-binding Protein (ChREBP) Expression in a Tissue-selective Manner

(2010) Karine Gauthier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) Regulates Adipose Tissue Accumulation and Adipocyte Insulin Sensitivityin Vivo

(2010) Maria M. Sutanto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

(2008) Sarah K Knutson et al.   EMBO JOURNAL

Cooperative regulation in development by SMRT and FOXP1

(2008) K. Jepsen et al.   GENES & DEVELOPMENT

SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis

(2008) R. R. Nofsinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo

(2008) I. Astapova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA