Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity

ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin- 2

(2012) A. von Thun et al.   JOURNAL OF CELL SCIENCE

Dynamic regulation of GEF-H1 localization at microtubules by Par1b/MARK2

(2011) Yuta Yoshimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Polarity-regulating Kinase Partitioning-defective 1b (PAR1b) Phosphorylates Guanine Nucleotide Exchange Factor H1 (GEF-H1) to Regulate RhoA-dependent Actin Cytoskeletal Reorganization

(2011) Yukie Yamahashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells

(2009) K. Paňková et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

GEF-H1 Mediates Tumor Necrosis Factor-α-induced Rho Activation and Myosin Phosphorylation

(2009) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guanine Nucleotide Exchange Factor-H1 Regulates Cell Migration via Localized Activation of RhoA at the Leading Edge

(2009) Perihan Nalbant et al.   MOLECULAR BIOLOGY OF THE CELL

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Cell fate decisions are specified by the dynamic ERK interactome

(2009) Alex von Kriegsheim et al.   NATURE CELL BIOLOGY

Rac and Rho driving tumor invasion: who's at the wheel?

(2009) Marc Symons et al.   GENOME BIOLOGY

ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA

(2008) Shuh-hei Fujishiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

GEF-H1 Couples Nocodazole-induced Microtubule Disassembly to Cell Contractility via RhoA

(2008) Yuan-Chen Chang et al.   MOLECULAR BIOLOGY OF THE CELL