Regulation of the Follistatin Gene by RSPO-LGR4 Signaling via Activation of the WNT/ -Catenin Pathway in Skeletal Myogenesis

Fibronectin Regulates Wnt7a Signaling and Satellite Cell Expansion

(2013) C. Florian Bentzinger et al.   Cell Stem Cell

The structural basis of R-spondin recognition by LGR5 and RNF43

(2013) P.-H. Chen et al.   GENES & DEVELOPMENT

Structural basis for R-spondin recognition by LGR4/5/6 receptors

(2013) D. Wang et al.   GENES & DEVELOPMENT

Leucine-rich repeat-containing G-protein coupled receptor 5/GPR49 activates G12/13-Rho GTPase pathway

(2013) Mi So Kwon et al.   MOLECULES AND CELLS

Structure of Stem Cell Growth Factor R-spondin 1 in Complex with the Ectodomain of Its Receptor LGR5

(2013) Weng Chuan Peng et al.   Cell Reports

The R-spondin family of proteins: Emerging regulators of WNT signaling

(2012) Yong-Ri Jin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

(2012) Catherine E. Winbanks et al.   JOURNAL OF CELL BIOLOGY

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

(2012) Huai-Xiang Hao et al.   NATURE

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5

(2012) Heinz Ruffner et al.   PLoS One

Wnt signaling in myogenesis

(2012) Julia von Maltzahn et al.   TRENDS IN CELL BIOLOGY

The R-spondin protein family

(2012) Wim BM de Lau et al.   GENOME BIOLOGY

The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal–mesenchymal interaction

(2011) Yong-Ri Jin et al.   DEVELOPMENTAL BIOLOGY

Rspo3 Binds Syndecan 4 and Induces Wnt/PCP Signaling via Clathrin-Mediated Endocytosis to Promote Morphogenesis

(2011) Bisei Ohkawara et al.   DEVELOPMENTAL CELL

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling

(2011) Andrei Glinka et al.   EMBO REPORTS

A WNT/β-Catenin Signaling Activator, R-spondin, Plays Positive Regulatory Roles during Skeletal Myogenesis

(2011) Xiang Hua Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Muscle Mass by Follistatin and Activins

(2010) Se-Jin Lee et al.   MOLECULAR ENDOCRINOLOGY

Loss-of-function point mutations and two-furin domain derivatives provide insights about R-spondin2 structure and function

(2009) Sheng-Jian Li et al.   CELLULAR SIGNALLING

Regulation of bone formation and remodeling by G-protein-coupled receptor 48

(2009) J. Luo et al.   DEVELOPMENT

Embryonic and fetal limb myogenic cells are derived from developmentally distinct progenitors and have different requirements for  -catenin

(2009) D. A. Hutcheson et al.   GENES & DEVELOPMENT

Follistatin Gene Delivery Enhances Muscle Growth and Strength in Nonhuman Primates

(2009) J. Kota et al.   Science Translational Medicine

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

(2008) Andrew S. Brack et al.   Cell Stem Cell

WNT11 acts as a directional cue to organize the elongation of early muscle fibres

(2008) Jérôme Gros et al.   NATURE

Lgr5 marks cycling, yet long-lived, hair follicle stem cells

(2008) Viljar Jaks et al.   NATURE GENETICS

Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

(2007) Masashi Nakatani et al.   FASEB JOURNAL