The Hypoxia-Inducible Factor-C/EBP  Axis Controls Ethanol-Mediated Hepcidin Repression

Hypoxia-Inducible Factor-2  Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis

(2012) X. Xue et al.   CANCER RESEARCH

Hypoxia inhibits hepcidin expression in HuH7 hepatoma cells via decreased SMAD4 signaling

(2011) Timothy B. Chaston et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression

(2011) V. R. Gordeuk et al.   BLOOD

Downregulating hypoxia-inducible factor-2α improves the efficacy of doxorubicin in the treatment of hepatocellular carcinoma

(2011) Changjun He et al.   CANCER SCIENCE

Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies

(2011) Yin Wang et al.   Cell Stem Cell

Hypoxia-Inducible Factor-2α Mediates the Adaptive Increase of Intestinal Ferroportin During Iron Deficiency in Mice

(2011) Matthew Taylor et al.   GASTROENTEROLOGY

Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis

(2011) M. Mastrogiannaki et al.   HAEMATOLOGICA

Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis

(2011) Aijuan Qu et al.   HEPATOLOGY

Intestinal Hypoxia-inducible Factor-2α (HIF-2α) Is Critical for Efficient Erythropoiesis

(2011) Erik R. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transferrin receptor 2 is crucial for iron sensing in human hepatocytes

(2010) Chiara Rapisarda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project

(2010) A. Piperno et al.   BLOOD

Elimination of C/EBPα through the ubiquitin-proteasome system promotes the development of liver cancer in mice

(2010) Guo-Li Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepcidin Regulation in Wild-Type and Hfe Knockout Mice in Response to Alcohol Consumption: Evidence for an Alcohol-Induced Hypoxic Response

(2009) Mandy L. Heritage et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Ablation of ARNT/HIF1β in Liver Alters Gluconeogenesis, Lipogenic Gene Expression, and Serum Ketones

(2009) Xiaohui L. Wang et al.   Cell Metabolism

Activated macrophages induce hepcidin expression in HuH7 hepatoma cells

(2009) P. Matak et al.   HAEMATOLOGICA

Evidence for a Lack of a Direct Transcriptional Suppression of the Iron Regulatory Peptide Hepcidin by Hypoxia-Inducible Factors

(2009) Melanie Volke et al.   PLoS One

Oxidative Stress and Alcoholic Liver Disease

(2009) Defeng Wu et al.   SEMINARS IN LIVER DISEASE

Is the iron regulatory hormone hepcidin a risk factor for alcoholic liver disease?

(2009) Duygu-Dee Harrison-Findik   WORLD JOURNAL OF GASTROENTEROLOGY

Is iron overload in alcohol-related cirrhosis mediated byhepcidin?

(2009) Tariq Iqbal et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Oxygen homeostasis

(2009) Gregg L. Semenza   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Regulation of liver hepcidin expression by alcohol in vivo does not involve Kupffer cell activation or TNF-α signaling

(2008) Duygu Dee Harrison-Findik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

(2008) L. Kautz et al.   BLOOD

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBP 

(2008) J. P. Pinto et al.   BLOOD

The VHL tumor suppressor and HIF: insights from genetic studies in mice

(2008) P P Kapitsinou et al.   CELL DEATH AND DIFFERENTIATION

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

Role of Iron Deficiency and Overload in the Pathogenesis of Diabetes and Diabetic Complications

(2008) Qiuju Liu et al.   CURRENT MEDICINAL CHEMISTRY

2-Oxoglutarate-dependent oxygenases control hepcidin gene expression

(2008) Georgia G. Braliou et al.   JOURNAL OF HEPATOLOGY

Synergistic interaction between excess hepatic iron and alcohol ingestion in hepatic mutagenesis

(2008) George A. Asare et al.   TOXICOLOGY

Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells

(2007) T Chaston et al.   GUT