PERK Is Required in the Adult Pancreas and Is Essential for Maintenance of Glucose Homeostasis

Regulated and Reversible Induction of Adult Human  -Cell Replication

(2011) K. K. Takane et al.   DIABETES

The Cell Biology of the Unfolded Protein Response

(2011) J. Alan Diehl et al.   GASTROENTEROLOGY

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

(2010) Nathalie M. Fiaschi-Taesch et al.   DIABETES

Mechanism of Hyperinsulinism in Short-chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Involves Activation of Glutamate Dehydrogenase

(2010) Changhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PERK Activation at Low Glucose Concentration Is Mediated by SERCA Pump Inhibition and Confers Preemptive Cytoprotection to Pancreatic β-Cells

(2010) Claire E. Moore et al.   MOLECULAR ENDOCRINOLOGY

PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage

(2010) E Bobrovnikova-Marjon et al.   ONCOGENE

PERK in beta cell biology and insulin biogenesis

(2010) Douglas R. Cavener et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation

(2009) Daorong Feng et al.   BMC CELL BIOLOGY

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

Secondary Consequences of β Cell Inexcitability: Identification and Prevention in a Murine Model of KATP-Induced Neonatal Diabetes Mellitus

(2009) Maria Sara Remedi et al.   Cell Metabolism

Survey of the Human Pancreatic  -Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D1 in Enhancing Human  -Cell Replication and Function In Vivo

(2009) N. Fiaschi-Taesch et al.   DIABETES

Cyclin D2 Protein Stability Is Regulated in Pancreatic β-Cells

(2009) Lu Mei He et al.   MOLECULAR ENDOCRINOLOGY

PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation

(2008) E. Bobrovnikova-Marjon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA